Three-step,“one-pot” radiosynthesis of 6-fluoro-3, 4-dihydroxy-l-phenylalanine by isotopic exchange

FM Wagner, J Ermert, HH Coenen - Journal of nuclear medicine, 2009 - Soc Nuclear Med
The 18 F-labeled aromatic amino acid 6-fluoro-3,4-dihydroxy-l-phenylalanine (6- 18 F-fluoro-l-DOPA)
is widely used as a radiopharmaceutical in neurologic and oncologic PET. In this …

(S)-4-(3-18F-fluoropropyl)-l-glutamic acid: an 18F-labeled tumor-specific probe for PET/CT imaging—dosimetry

…, BJ Krause, FP Graner, FM Wagner… - Journal of Nuclear …, 2013 - Soc Nuclear Med
The glutamic acid derivative (S)-4-(3- 18 F-Fluoropropyl)-l-glutamic acid ( 18 F-FSPG, alias
BAY 94-9392), a new PET tracer for the detection of malignant diseases, displayed promising …

Neurotrophin expression is not affected in uteri of women with adenomyosis

ML Barcena de Arellano, MF Wagner… - Journal of Molecular …, 2012 - Springer
To investigate the involvement of neurotrophins and nerve fibres in the pathogenesis of
adenomyosis, we performed a retrospective, clinical study. Hysterectomy specimens from 40 …

Biodistribution and radiation dosimetry in healthy volunteers of a novel tumour-specific probe for PET/CT imaging: BAY 85-8050

K Smolarz, BJ Krause, FP Graner, FM Wagner… - European journal of …, 2013 - Springer
Purpose Novel tracers for the diagnosis of malignant disease with PET and PET/CT are
being developed as the most commonly used 18 F deoxyglucose (FDG) tracer shows certain …

Evolutionary constraint and innovation across hundreds of placental mammals

…, L Ryan, R Swofford, A Valenzuela, F Wagner… - Science, 2023 - science.org
Zoonomia is the largest comparative genomics resource for mammals produced to date. By
aligning genomes for 240 species, we identify bases that, when mutated, are likely to affect …

Mammalian evolution of human cis-regulatory elements and transcription factor binding sites

…, E Teeling, J Turner-Maier, A Valenzuela, F Wagner… - Science, 2023 - science.org
Understanding the regulatory landscape of the human genome is a long-standing objective
of modern biology. Using the reference-free alignment across 241 mammalian genomes …

[HTML][HTML] In vivo genome editing as a potential treatment strategy for inherited retinal dystrophies

M Yanik, B Müller, F Song, J Gall, F Wagner… - Progress in retinal and …, 2017 - Elsevier
In vivo genome editing represents an emerging field in the treatment of monogenic disorders,
as it may constitute a solution to the current hurdles in classic gene addition therapy, which …

[HTML][HTML] Organotypic cultures of adult mouse retina: morphologic changes and gene expression

B Müller, F Wagner, B Lorenz… - … ophthalmology & visual …, 2017 - tvst.arvojournals.org
Purpose: The purpose of this study was characterization of adult murine neuroretina in organ
culture to investigate its suitability for use in preclinical therapeutic applications. In retinal …

Correlating habenular subnuclei in rat and mouse by using topographic, morphological, and cytochemical criteria

F Wagner, T Stroh, RW Veh - Journal of Comparative …, 2014 - Wiley Online Library
The mammalian habenulae consist of medial (MHb) and lateral (LHb) nuclear complexes.
Especially the LHb has received much interest because it has been recognized as the …

Microarray analysis of transcripts with elevated expressions in the rat medial or lateral habenula suggest fast GABAergic excitation in the medial habenula and …

F Wagner, R Bernard, C Derst, L French… - Brain Structure and …, 2016 - Springer
In vertebrates the “anti-reward-system” mainly is represented by the habenula and its medial
(MHb) and especially lateral (LHb) complexes. Considerable knowledge has accumulated …