Current methods for attaching targeting ligands to liposomes and nanoparticles
L Nobs, F Buchegger, R Gurny, E Allémann - Journal of pharmaceutical …, 2004 - Elsevier
Liposomes and nanoparticles have emerged as versatile carrier systems for delivering active
molecules in the organism. These colloidal particles have demonstrated enhanced efficacy …
molecules in the organism. These colloidal particles have demonstrated enhanced efficacy …
18F‐choline and/or 11C‐acetate positron emission tomography: detection of residual or progressive subclinical disease at very low prostate‐specific antigen values …
H Vees, F Buchegger, S Albrecht, H Khan… - BJU …, 2007 - Wiley Online Library
OBJECTIVES To assess the value of positron emission tomography (PET)/computed tomography
(CT) with either 18 F‐choline and/or 11 C‐acetate, of residual or recurrent tumour after …
(CT) with either 18 F‐choline and/or 11 C‐acetate, of residual or recurrent tumour after …
Auger radiation targeted into DNA: a therapy perspective
F Buchegger, F Perillo-Adamer, YM Dupertuis… - European journal of …, 2006 - Springer
Background Auger electron emitters that can be targeted into DNA of tumour cells represent
an attractive systemic radiation therapy goal. In the situation of DNA-associated decay, the …
an attractive systemic radiation therapy goal. In the situation of DNA-associated decay, the …
Use of radiolabelled monoclonal anti-CEA antibodies for the detection of human carcinomas by external photoscanning and tomoscintigraphy
JP Mach, F Buchegger, M Forni, J Ritschard, C Berche… - Immunology today, 1981 - cell.com
Paul Ehrlich's inspired concept of'magic bullets' for the cure (~ f diseases has beer~
revitalized by recent advances in immunology j. In parlicular, the development of ceil fusion …
revitalized by recent advances in immunology j. In parlicular, the development of ceil fusion …
The in vivo performance of magnetic particle-loaded injectable, in situ gelling, carriers for the delivery of local hyperthermia
…, H Hofmann, D Ruefenacht, F Bosman, F Buchegger… - Biomaterials, 2010 - Elsevier
We investigated the use of in situ implant formation that incorporates superparamagnetic iron
oxide nanoparticles (SPIONs) as a form of minimally invasive treatment of cancer lesions …
oxide nanoparticles (SPIONs) as a form of minimally invasive treatment of cancer lesions …
Biodegradable nanoparticles for direct or two-step tumor immunotargeting
L Nobs, F Buchegger, R Gurny… - Bioconjugate …, 2006 - ACS Publications
In this study, selective cancer cell targeting of biodegradable poly(lactic acid) (PLA)
nanoparticles (NPs) has been investigated in vitro. SKOV-3 (HER2 positive) ovarian cancer and …
nanoparticles (NPs) has been investigated in vitro. SKOV-3 (HER2 positive) ovarian cancer and …
Antigenic sites in carcinoembryonic antigen
…, Å Larsson, R Ghosh, O Bormer, F Buchegger… - Cancer Research, 1989 - AACR
The epitope reactivities of 52 well-characterized monoclonal antibodies (Mabs) against
carcinoembryonic antigen from 11 different research groups were studied using competitive solid…
carcinoembryonic antigen from 11 different research groups were studied using competitive solid…
Poly (lactic acid) nanoparticles labeled with biologically active Neutravidin™ for active targeting
L Nobs, F Buchegger, R Gurny, E Allémann - European journal of …, 2004 - Elsevier
In this study, NeutrAvidin™ was covalently bound to the surface of poly(dl-lactic acid) (PLA)
nanoparticles, with the aim of attaching targeting compounds, such as proteins, to their …
nanoparticles, with the aim of attaching targeting compounds, such as proteins, to their …
11C-acetate PET in the early evaluation of prostate cancer recurrence
S Albrecht, F Buchegger, D Soloviev, H Zaidi… - European journal of …, 2007 - Springer
Purpose The first aim of the study was to investigate the diagnostic potential of 11 C-acetate
PET in the early detection of prostate cancer recurrence. A second aim was the evaluation of …
PET in the early detection of prostate cancer recurrence. A second aim was the evaluation of …
Radiolabeled neurotensin analog, 99mTc-NT-XI, evaluated in ductal pancreatic adenocarcinoma patients
F Buchegger, F Bonvin, M Kosinski… - Journal of Nuclear …, 2003 - Soc Nuclear Med
The study aim was to assess the safety, biodistribution, tissue kinetics, and tumor uptake of
the 99m Tc-labeled neurotensin (NT) analog NT-XI. Methods: Four patients presenting ductal …
the 99m Tc-labeled neurotensin (NT) analog NT-XI. Methods: Four patients presenting ductal …