Diagnostic performance of 18F-FET PET in newly diagnosed cerebral lesions suggestive of glioma

…, T Beez, HH Coenen, FW Floeth… - Journal of nuclear …, 2013 - Soc Nuclear Med
The aim of this study was to assess the clinical value of O-(2- 18 F-fluoroethyl)-l-tyrosine ( 18
F-FET) PET in the initial diagnosis of cerebral lesions suggestive of glioma. Methods: In a …

Prognostic value of O-(2-18F-fluoroethyl)-L-tyrosine PET and MRI in low-grade glioma

FW Floeth, D Pauleit, M Sabel, G Stoffels… - Journal of nuclear …, 2007 - Soc Nuclear Med
In glioma of World Health Organization (WHO) grade II (low-grade glioma), the natural
course of a particular patient is not predictable and the treatment strategy is controversial. We …

Comparison of 18F-FET and 18F-FDG PET in brain tumors

D Pauleit, G Stoffels, A Bachofner, FW Floeth… - Nuclear medicine and …, 2009 - Elsevier
The purpose of this study was to compare the diagnostic value of positron emission
tomography (PET) using [ 18 F]-fluorodeoxyglucose ( 18 F-FDG) and O-(2-[ 18 F]fluoroethyl)-l-…

Finding the anaplastic focus in diffuse gliomas: the value of Gd-DTPA enhanced MRI, FET-PET, and intraoperative, ALA-derived tissue fluorescence

C Ewelt, FW Floeth, J Felsberg, HJ Steiger… - Clinical neurology and …, 2011 - Elsevier
OBJECTIVE: Diffuse gliomas may harbor anaplastic foci which affect prognosis and determine
adjuvant therapies. Such foci are not always detected by contrast-enhancement on MRI. …

18F-FET PET differentiation of ring-enhancing brain lesions

FW Floeth, D Pauleit, M Sabel… - Journal of Nuclear …, 2006 - Soc Nuclear Med
The aim of this study was to explore the differential diagnostic value of PET using the amino
acid O-(2- 18 F-fluoroethyl)-l-tyrosine ( 18 F-FET) in patients with newly diagnosed solitary …

The impact of fluorescence guidance on spinal intradural tumour surgery

SO Eicker, FW Floeth, M Kamp, HJ Steiger… - European spine …, 2013 - Springer
Purpose 5-Aminolevulinic acid (5-ALA)-based fluorescence-guided surgery was shown to
be beneficial for cerebral malignant gliomas. Extension of this technique for resection of …

Local inflammation and devascularization—in vivo mechanisms of the “bystander effect” in VPC-mediated HSV-Tk/GCV gene therapy for human malignant glioma

FW Floeth, N Shand, H Bojar, HB Prisack… - Cancer gene …, 2001 - nature.com
Somatic gene therapy with the herpes simplex virus type I thymidine kinase gene/ganciclovir
(HSV-Tk/GCV) system and murine retroviral vector producer cells (VPCs) was introduced …

[HTML][HTML] Impact of the surgical strategy on the incidence of C5 nerve root palsy in decompressive cervical surgery

…, M Mohme, KC Mende, SO Eicker, FW Floeth - PLoS One, 2017 - journals.plos.org
Objective Our aim was to identify the impact of different surgical strategies on the incidence
of C5 palsy. Background Degenerative cervical spinal stenosis is a steadily increasing …

Impact of spinal cord compression from intradural and epidural spinal tumors on perioperative symptoms—implications for surgical decision making

…, K Beseoglu, J Hagedorn, HJ Steiger, FW Floeth… - Neurosurgical …, 2017 - Springer
Spinal cord or cauda equina compression (SCC) is an increasing challenge in clinical oncology
due to a higher prevalence of long-term cancer survivors. Our aim was to determine the …

Clinical value of O-(2-[18F]-fluoroethyl)-L-tyrosine positron emission tomography in patients with low-grade glioma

M Rapp, FW Floeth, J Felsberg, HJ Steiger, M Sabel… - Neurosurgical …, 2013 - thejns.org
Progress in morphological imaging has facilitated the diagnosis of low-grade glioma (LGG)
and plays a decisive role in therapeutic decisions. To date, the method of choice is contrast-…