User profiles for Frank Rosch

Frank Rösch

Verified email at uni-mainz.de
Cited by 14616

Correlation Between Dopamine D2 Receptors in the Ventral Striatum and Central Processing of Alcohol Cues and Craving

…, MN Smolka, F Rösch… - American Journal of …, 2004 - Am Psychiatric Assoc
OBJECTIVE: Alcohol and other drugs of abuse stimulate dopamine release in the ventral
striatum, which includes the nucleus accumbens, a core region of the brain reward system, and …

Processing of generator-produced 68Ga for medical application

…, M Jahn, M Jennewein, F Rösch - Journal of Nuclear …, 2007 - Soc Nuclear Med
The 68 Ge/ 68 Ga generator provides an excellent source of positron-emitting 68 Ga.
However, newly available “ionic” 68 Ge/ 68 Ga radionuclide generators are not necessarily …

Correlation of Alcohol Craving With Striatal Dopamine Synthesis Capacity and D2/3 Receptor Availability: A Combined [18F]DOPA and [18F]DMFP PET Study in …

…, MN Smolka, F Rösch… - American Journal of …, 2005 - Am Psychiatric Assoc
OBJECTIVE: In abstinent alcoholic patients, a low availability of dopamine D 2/3 receptors
in the ventral striatum and adjacent putamen was associated with a high level of craving for …

Association of Low Striatal Dopamine D 2 Receptor Availability With Nicotine Dependence Similar to That Seen With Other Drugs of Abuse

…, T Dielentheis, LG Schmidt, F Rösch… - American Journal of …, 2008 - Am Psychiatric Assoc
Objective: All drugs of abuse induce a phasic dopamine release within the striatum that does
not undergo habituation. Prolonged substance consumption impairs the natural function of …

High opiate receptor binding potential in the human lateral pain system

…, R Rolke, S Höhnemann, M Piel, F Rösch… - Neuroimage, 2006 - Elsevier
To determine how opiate receptor distribution is co-localized with the distribution of nociceptive
areas in the human brain, eleven male healthy volunteers underwent one PET scan with …

A Triazacyclononane‐Based Bifunctional Phosphinate Ligand for the Preparation of Multimeric 68Ga Tracers for Positron Emission Tomography

…, N Loktionova, PJ Riss, F Rösch… - … A European Journal, 2010 - Wiley Online Library
For application in positron emission tomography (PET), PrP9, a N,N′,N′′‐trisubstituted
triazacyclononane with methyl(2‐carboxyethyl)phosphinic acid pendant arms, was …

Generator-based PET radiopharmaceuticals for molecular imaging of tumours: on the way to THERANOSTICS

F Rösch, RP Baum - Dalton transactions, 2011 - pubs.rsc.org
Generator-derived radionuclides for PET/CT imaging are promising for optimizing targeted
radiotherapy by an individual patient-based approach, applying pre-therapeutic evaluation, …

Positron emission tomography in CNS drug discovery and drug monitoring

M Piel, I Vernaleken, F Rösch - Journal of medicinal chemistry, 2014 - ACS Publications
Molecular imaging methods such as positron emission tomography (PET) are increasingly
involved in the development of new drugs. Using radioactive tracers as imaging probes, PET …

[PDF][PDF] Measurement of pharmacokinetics of yttrium-86 radiopharmaceuticals with PET and radiation dose calculation of analogous yttrium-90 radiotherapeutics

H Herzog, F Rösch, G Stöcklin, C Lueders… - Journal of Nuclear …, 1993 - Soc Nuclear Med
RESULTS Figure 1 (left part) displays an anterior view of the pa tient's body from the head
down to the knee. As all coronal sections are summarized here, this image is equivalent to the …

A 44Ti/44Sc radionuclide generator for potential application of 44Sc-based PET-radiopharmaceuticals

DV Filosofov, NS Loktionova, F Rösch - rca-Radiochimica Acta, 2010 - degruyter.com
44 Ti/ 44 Sc radionuclide generators are of interest for molecular imaging. The 3.97 h half-life
of 44 Sc and its high positron branching of 94% may stimulate the application of 44 Sc …