Comparative evaluation of the translocator protein radioligands 11C-DPA-713, 18F-DPA-714, and 11C-PK11195 in a rat model of acute neuroinflammation
…, F Dollé, B Kuhnast, F Hinnen… - Journal of Nuclear …, 2009 - Soc Nuclear Med
Overexpression of the translocator protein, TSPO (18 kDa), formerly known as the peripheral
benzodiazepine receptor, is a hallmark of activation of cells of monocytic lineage (microglia …
benzodiazepine receptor, is a hallmark of activation of cells of monocytic lineage (microglia …
Decreased presynaptic dopamine function in the left caudate of depressed patients with affective flattening and psychomotor retardation
…, E Artiges, F Dollé, F Hinnen… - American Journal of …, 2001 - Am Psychiatric Assoc
OBJECTIVE: The study assessed striatal presynaptic dopamine function in patients with
different subtypes of depression. METHOD: Magnetic resonance imaging and positron emission …
different subtypes of depression. METHOD: Magnetic resonance imaging and positron emission …
In vivo imaging of oligonucleotides with positron emission tomography
…, F Dollé, JR Deverre, A Jobert, F Hinnen… - Nature …, 1998 - research.uniupo.it
The data reported in this study show (1) that the proposed radiolabelling methods does not
modify the capcity of the antisense oligonucleotide to hybridize to its target complemetary …
modify the capcity of the antisense oligonucleotide to hybridize to its target complemetary …
Fluorine-18-Labeled Phospholipid Quantum Dot Micelles for in Vivo Multimodal Imaging from Whole Body to Cellular Scales
…, B Thézé, K Gombert, B Mahler, F Hinnen… - Bioconjugate …, 2008 - ACS Publications
We have designed new nanoprobes applicable for both positron emission tomography (PET)
and optical fluorescence in vivo imaging. Fluorine-18, which is commonly used for clinical …
and optical fluorescence in vivo imaging. Fluorine-18, which is commonly used for clinical …
1-[3-(2-[18F]Fluoropyridin-3-yloxy)propyl]pyrrole-2,5-dione: Design, Synthesis, and Radiosynthesis of a New [18F]Fluoropyridine-Based Maleimide Reagent for the …
B De Bruin, B Kuhnast, F Hinnen… - Bioconjugate …, 2005 - ACS Publications
FPyME (1-[3-(2-fluoropyridin-3-yloxy)propyl]pyrrole-2,5-dione) was designed as a [ 18 F]fluoropyridine-based
maleimide reagent for the prosthetic labeling of peptides and proteins via …
maleimide reagent for the prosthetic labeling of peptides and proteins via …
Synthesis and Nicotinic Acetylcholine Receptor in Vivo Binding Properties of 2-Fluoro-3-[2(S)-2-azetidinylmethoxy]pyridine: A New Positron Emission Tomography …
F Dollé, L Dolci, H Valette, F Hinnen… - Journal of medicinal …, 1999 - ACS Publications
The lead compound of a new series of 3-pyridyl ethers, the azetidine derivative A-85380 (3-[(S)-2-azetidinylmethoxy]pyridine),
is a potent and selective ligand for the human α4β2 …
is a potent and selective ligand for the human α4β2 …
Radiosynthesis of [18F]DPA‐714, a selective radioligand for imaging the translocator protein (18 kDa) with PET
A Damont, F Hinnen, B Kuhnast… - Journal of Labelled …, 2008 - Wiley Online Library
Recently, a novel series of 2‐phenylpyrazolo[1,5‐a]pyrimidineacetamides has been reported
as selective ligands of the translocator protein (18 kDa). Within this series, DPA‐714 (N,N‐…
as selective ligands of the translocator protein (18 kDa). Within this series, DPA‐714 (N,N‐…
6‐[18F]Fluoro‐L‐DOPA by radiofluorodestannylation: a short and simple synthesis of a new labelling precursor
F Dolle, S Demphel, F Hinnen… - Journal of Labelled …, 1998 - Wiley Online Library
This paper describes a short and simple synthesis of a new fully protected stannylated
precursor, namely N‐(tert‐butoxycarbonyl)‐3,4‐di(tert‐butoxycarbonyloxy)‐6‐trimethylstannyl‐L‐…
precursor, namely N‐(tert‐butoxycarbonyl)‐3,4‐di(tert‐butoxycarbonyloxy)‐6‐trimethylstannyl‐L‐…
Encapsulated GDNF-producing C2C12 cells for Parkinson's disease: a pre-clinical study in chronic MPTP-treated baboons
Glial cell line-derived neurotrophic factor (GDNF), a potent neurotrophic factor with restorative
effects in a variety of rodent and primate models of Parkinson's disease (PD), could be of …
effects in a variety of rodent and primate models of Parkinson's disease (PD), could be of …
[18F] DPA-714,[18F] PBR111 and [18F] FEDAA1106—Selective radioligands for imaging TSPO 18 kDa with PET: Automated radiosynthesis on a TRACERLAb FX-FN …
B Kuhnast, A Damont, F Hinnen, T Catarina… - Applied Radiation and …, 2012 - Elsevier
Imaging of TSPO 18kDa with PET is more and more considered as a relevant biomarker of
inflammation in numerous diseases. Development of new radiotracers for TSPO 18kDa has …
inflammation in numerous diseases. Development of new radiotracers for TSPO 18kDa has …