Functional significance of cell volume regulatory mechanisms

F Lang, GL Busch, M Ritter, H Volkl… - Physiological …, 1998 - journals.physiology.org
FLORIAN LANGFLORIAN LANGLang, Florian, Gillian L. Busch, Markus Ritter, Harald
Völkl, Siegfried Waldegger, Erich Gulbins, and Dieter Häussinger. Functional Significance of Cell …

(Patho) physiological significance of the serum-and glucocorticoid-inducible kinase isoforms

F Lang, C Bohmer, M Palmada… - Physiological …, 2006 - journals.physiology.org
The serum- and glucocorticoid-inducible kinase-1 (SGK1) is ubiquitously expressed and
under genomic control by cell stress (including cell shrinkage) and hormones (including gluco- …

Na+-d-glucose Cotransporter SGLT1 is Pivotal for Intestinal Glucose Absorption and Glucose-Dependent Incretin Secretion

…, HE Parker, FM Gribble, F Reimann, F Lang… - Diabetes, 2012 - Am Diabetes Assoc
To clarify the physiological role of Na + -d-glucose cotransporter SGLT1 in small intestine and
kidney, Sglt1 −/− mice were generated and characterized phenotypically. After gavage of d…

Cloning and characterization of two human polyspecific organic cation transporters

…, U Karbach, S Quester, C Baumann, F Lang… - DNA and cell …, 1997 - liebertpub.com
Previously we cloned a polyspecific transporter from rat (rOCT1) that is expressed in renal
proximal tubules and hepatocytes and mediates electrogenic uptake of organic cations with …

The low-affinity monocarboxylate transporter MCT4 is adapted to the export of lactate in highly glycolytic cells

KS Dimmer, B FRIEDRICH, F Lang… - Biochemical …, 2000 - portlandpress.com
Transport of lactate and other monocarboxylates in mammalian cells is mediated by a family
of transporters, designated monocarboxylate transporters (MCTs). The MCT4 member of …

Mechanisms of suicidal erythrocyte death

K Lang, P Lang, C Bauer, C Duranton… - Cellular Physiology and …, 2005 - karger.com
Erythrocyte injury such as osmotic shock, oxidative stress or energy depletion stimulates the
formation of prostaglandin E 2 through activation of cyclooxygenase which in turn activates …

Ceramide accumulation mediates inflammation, cell death and infection susceptibility in cystic fibrosis

…, KW Schmid, M Weller, B Tümmler, F Lang… - Nature medicine, 2008 - nature.com
Microbial lung infections are the major cause of morbidity and mortality in the hereditary
metabolic disorder cystic fibrosis, yet the molecular mechanisms leading from the mutation of …

Mechanisms and significance of cell volume regulation

F Lang - Journal of the American college of nutrition, 2007 - Taylor & Francis
Survival of human and animal cells requires avoidance of excessive alterations of cell
volume. The osmolarity amassed by cellular accumulation of organic substances must be …

Liver cell death and anemia in Wilson disease involve acid sphingomyelinase and ceramide

PA Lang, M Schenck, JP Nicolay, JU Becker… - Nature medicine, 2007 - nature.com
Wilson disease is caused by accumulation of Cu 2+ in cells, which results in liver cirrhosis
and, occasionally, anemia. Here, we show that Cu 2+ triggers hepatocyte apoptosis through …

Role of Ca2+-activated K+ channels in human erythrocyte apoptosis

PA Lang, S Kaiser, S Myssina… - … of Physiology-Cell …, 2003 - journals.physiology.org
Exposure of erythrocytes to the Ca 2+ ionophore ionomycin has recently been shown to
induce cell shrinkage, cell membrane blebbing, and breakdown of phosphatidylserine …