Based on the recent literature and collective experience, an international consortium developed
revised guidelines for the diagnosis of behavioural variant frontotemporal dementia. The …

The NINCDS–ADRDA and the DSM-IV-TR criteria for Alzheimer's disease (AD) are the
prevailing diagnostic standards in research; however, they have now fallen behind the …

Alzheimer's disease (AD) is classically defined as a dual clinicopathological entity. The recent
advances in use of reliable biomarkers of AD that provide in-vivo evidence of the disease …

Eleven susceptibility loci for late-onset Alzheimer's disease (LOAD) were identified by previous
studies; however, a large portion of the genetic risk for this disease remains unexplained. …

In the past 8 years, both the International Working Group (IWG) and the US National Institute
on Aging–Alzheimer's Association have contributed criteria for the diagnosis of Alzheimer's …

The gene encoding apolipoprotein E (APOE) on chromosome 19 is the only confirmed
susceptibility locus for late-onset Alzheimer's disease. To identify other risk loci, we conducted a …

We sought to identify new susceptibility loci for Alzheimer's disease through a staged
association study (GERAD+) and by testing suggestive loci reported by the Alzheimer's Disease …

Background and Purpose—MRI is more sensitive than CT for detection of age-related white
matter changes (ARWMC). Most rating scales estimate the degree and distribution of …

Dementia is one of the major causes of dependency after stroke. The prevalence of poststroke
dementia (PSD)—defined as any dementia occurring after stroke—is likely to increase in …

We identified rare coding variants associated with Alzheimer's disease in a three-stage case–control
study of 85,133 subjects. In stage 1, we genotyped 34,174 samples using a whole-…