User profiles for Evan D. Morris

Evan Morris

Professor Radiology & Biomedical Imaging, Biomedical Engineering, Yale
Verified email at yale.edu
Cited by 7280

Consensus Nomenclature for in vivo Imaging of Reversibly Binding Radioligands

…, RP Maguire, MA Mintun, ED Morris… - Journal of Cerebral …, 2007 - journals.sagepub.com
… With this nomenclature, BP without subscript refers to the ‘true’ in vitro measurement of B
max /K D , and BP with subscripts refers to in vivo measurements that reflect, but typically do not …

Direct reconstruction of kinetic parameter images from dynamic PET data

ME Kamasak, CA Bouman, ED Morris… - IEEE transactions on …, 2005 - ieeexplore.ieee.org
Our goal in this paper is the estimation of kinetic model parameters for each voxel
corresponding to a dense three-dimensional (3-D) positron emission tomography (PET) image. …

Endotoxin-induced systemic inflammation activates microglia:[11C] PBR28 positron emission tomography in nonhuman primates

…, T Schafbauer, K Lim, T Kloczynski, ED Morris… - Neuroimage, 2012 - Elsevier
Microglia play an essential role in many brain diseases. Microglia are activated by local
tissue damage or inflammation, but systemic inflammation can also activate microglia. An …

[HTML][HTML] Reduced dopamine receptors and transporters but not synthesis capacity in normal aging adults: a meta-analysis

TM Karrer, AK Josef, R Mata, ED Morris… - Neurobiology of …, 2017 - Elsevier
Many theories of cognitive aging are based on evidence that dopamine (DA) declines with
age. Here, we performed a systematic meta-analysis of cross-sectional positron emission …

Horseradish peroxidase for the removal of carcinogenic aromatic amines from water

AM Klibanov, ED Morris - Enzyme and Microbial Technology, 1981 - Elsevier
A new method has been developed for the removal of carcinogenic aromatic amines from
industrial aqueous effluents. It includes the treatment of aqueous solutions containing the …

Sex differences in the brain's dopamine signature of cigarette smoking

…, HD Tagare, JM Sullivan, ED Morris - Journal of …, 2014 - Soc Neuroscience
Cigarette smoking is a major public health danger. Women and men smoke for different reasons
and cessation treatments, such as the nicotine patch, are preferentially beneficial to men…

[PDF][PDF] Kinetic modeling in positron emission tomography

ED Morris, CJ Endres, KC Schmidt… - … : The fundamentals of …, 2004 - bme.unc.edu
Positron emission tomography (PET) is a functional imaging technique that measures the
local concentration of an exogenous tracer molecule in the target tissue. Thus, given a time …

A linear model for estimation of neurotransmitter response profiles from dynamic PET data

MD Normandin, WK Schiffer, ED Morris - Neuroimage, 2012 - Elsevier
The parametric ntPET model (p-ntPET) estimates the kinetics of neurotransmitter release from
dynamic PET data with receptor–ligand radiotracers. Here we introduce a linearization (lp-…

Heterogeneous effects of alcohol on dopamine release in the striatum: a PET study

…, TE Cheng, SJ O'Connor, ED Morris - Alcoholism: Clinical …, 2007 - Wiley Online Library
Background: A dopaminergic response to alcohol in humans has not been demonstrated
consistently with positron emission tomography (PET). We hypothesized that the effect of …

Synthesis and evaluation of 11C-LY2795050 as a κ-opioid receptor antagonist radiotracer for PET imaging

…, J Masters, A Navarro, E Seest, ED Morris… - Journal of Nuclear …, 2013 - Soc Nuclear Med
Kappa-opioid receptors (KOR) are believed to be involved in the pathophysiology of depression,
anxiety disorders, drug abuse, and alcoholism. To date, only 1 tracer, the KOR agonist …