Enhanced permeability of the tumor vasculature allows macromolecules to enter the tumor
interstitial space, whereas the suppressed lymphatic filtration allows them to stay there. This …

Near-infrared (NIR) fluorescence imaging clinical studies have been reported in the literature
with six different devices that employ various doses of indocyanine green (ICG) as a non-…

The deep tissue propagation of near-infrared (NIR) light between 700–900 nm offers new
opportunities for diagnostic imaging when employing sensitive detection techniques and NIR …

The use of near-infrared (NIR) light to interrogate deep tissues has enormous potential for
molecular-based imaging when coupled with NIR excitable dyes. More than a decade has …

Purpose: To prospectively demonstrate the feasibility of using indocyanine green, a near-infrared
(NIR) fluorophore at the minimum dose needed for noninvasive optical imaging of …

The specificity of a novel epidermal growth factor (EGF)-Cy5.5 fluorescent optical probe in
the detection of EGF receptor (EGFr) was assessed using continuous-wave fluorescence …

Objective Fluorophore-labeled contrast imaging agents are moving toward clinical use for a
number of applications. The near-infrared dye IRDye 800CW is frequently used in its N-…

Targeted fluorescent molecular imaging probes may provide an optimal means of detecting
disease. Stable, organic fluorophores can be repeatedly excited in vivo by propagated light …

Mechanical stress is pervasive in egress routes of malignancy, yet the intrinsic effects of
force on tumour cells remain poorly understood. Here, we demonstrate that frictional force …

While the lymphatic system is increasingly associated with diseases of prevalence, study of
these diseases is difficult owing to the paucity of imaging techniques with the sensitivity and …