A functional genomics predictive network model identifies regulators of inflammatory bowel disease
A major challenge in inflammatory bowel disease (IBD) is the integration of diverse IBD data
sets to construct predictive models of IBD. We present a predictive model of the immune …
sets to construct predictive models of IBD. We present a predictive model of the immune …
Future deforestation in the Amazon and consequences for South American climate
Ongoing agricultural expansion in Amazonia and the surrounding areas of Brazil is expected
to continue over the next several decades as global food demand increases. The transition …
to continue over the next several decades as global food demand increases. The transition …
Impacts of climate change and deforestation on hydropower planning in the Brazilian Amazon
The Amazon Basin is Brazil’s next frontier for hydropower, but alterations to the water cycle
from climate change and deforestation could affect river flows fuelling electricity generation. …
from climate change and deforestation could affect river flows fuelling electricity generation. …
Comparison of glioblastoma (GBM) molecular classification methods
Glioblastoma (GBM) is the most aggressive and common form of brain cancer in adults.
GBM is characterized by poor survival and remarkably high tumors heterogeneity (both …
GBM is characterized by poor survival and remarkably high tumors heterogeneity (both …
Application of magnetic nanoparticle for controlled tissue assembly and tissue engineering
Magnetic nanoparticles have been subjected to extensive studies in the past few decades
owing to their promising potentials in biomedical applications. The versatile intrinsic …
owing to their promising potentials in biomedical applications. The versatile intrinsic …
Biomimetic whitlockite inorganic nanoparticles-mediated in situ remodeling and rapid bone regeneration
…, HL Jang, HY Ahn, HK Lee, J Park, E Lee, EA Lee… - Biomaterials, 2017 - Elsevier
Bone remodeling process relies on complex signaling pathway between osteoblasts and
osteoclasts and control mechanisms to achieve homeostasis of their growth and differentiation. …
osteoclasts and control mechanisms to achieve homeostasis of their growth and differentiation. …
[PDF][PDF] Genome-wide CRISPR-Cas9 screens reveal loss of redundancy between PKMYT1 and WEE1 in glioblastoma stem-like cells
…, P Hoellerbauer, RJ Davis, R Basom, EJ Girard, E Lee… - Cell reports, 2015 - cell.com
To identify therapeutic targets for glioblastoma (GBM), we performed genome-wide CRISPR-Cas9
knockout (KO) screens in patient-derived GBM stem-like cells (GSCs) and human …
knockout (KO) screens in patient-derived GBM stem-like cells (GSCs) and human …
Prediction of overall survival for patients with metastatic castration-resistant prostate cancer: development of a prognostic model through a crowdsourced challenge …
Background Improvements to prognostic models in metastatic castration-resistant prostate
cancer have the potential to augment clinical trial design and guide treatment strategies. In …
cancer have the potential to augment clinical trial design and guide treatment strategies. In …
Chondroitin sulfate-based biomineralizing surface hydrogels for bone tissue engineering
Chondroitin sulfate (CS) is the major component of glycosaminoglycan in connective tissue.
In this study, we fabricated methacrylated PEGDA/CS-based hydrogels with varying CS …
In this study, we fabricated methacrylated PEGDA/CS-based hydrogels with varying CS …
A therapeutic convection–enhanced macroencapsulation device for enhancing β cell viability and insulin secretion
…, JA Giraldo, Y Kudo, EA Lee, Y Lee… - Proceedings of the …, 2021 - National Acad Sciences
Islet transplantation for type 1 diabetes treatment has been limited by the need for lifelong
immunosuppression regimens. This challenge has prompted the development of …
immunosuppression regimens. This challenge has prompted the development of …