Quantitative tumor oxymetric images from 4D electron paramagnetic resonance imaging (EPRI): methodology and comparison with blood oxygen level‐dependent …

…, JN River, GS Karczmar, ED Barth… - … in Medicine: An …, 2003 - Wiley Online Library
This work presents a methodology for obtaining quantitative oxygen concentration images
in the tumor‐bearing legs of living C3H mice. The method uses high‐resolution electron …

Oxymetry deep in tissues with low-frequency electron paramagnetic resonance.

HJ Halpern, C Yu, M Peric, E Barth… - Proceedings of the …, 1994 - National Acad Sciences
We have measured the oxygen concentration in the body water of murine FSa and NFSa
fibrosarcomas using a new method for quantitative oxygen concentration determination deep in …

Baicalein attenuates oxidant stress in cardiomyocytes

…, CQ Li, L Dey, E Barth… - American Journal …, 2002 - journals.physiology.org
Flavonoids within Scutellaria baicalensis may be potent antioxidants on the basis of our
studies of S. baicalensis extract. To further this work, we studied the antioxidative effects of …

Electron paramagnetic resonance oxygen images correlate spatially and quantitatively with Oxylite oxygen measurements

M Elas, KH Ahn, A Parasca, ED Barth, D Lee… - Clinical Cancer …, 2006 - AACR
Tumor oxygenation predicts cancer therapy response and malignant phenotype. This has
spawned a number of oxymetries. Comparison of different oxymetries is crucial for the …

Oxygen-guided radiation therapy

B Epel, MC Maggio, ED Barth, RC Miller… - International Journal of …, 2019 - Elsevier
Purpose It has been known for over 100 years that tumor hypoxia, a near-universal characteristic
of solid tumors, decreases the curative effectiveness of radiation therapy. However, to …

Electron spin relaxation of triarylmethyl radicals in fluid solution

…, SS Eaton, GR Eaton, C Mailer, E Barth… - Journal of Magnetic …, 2001 - Elsevier
Electron spin relaxation times of a Nycomed triarylmethyl radical (sym-trityl) in water, 1:1
water:glycerol, and 1:9 water:glycerol were measured at L-band, S-band, and X-band by pulsed …

Electron paramagnetic resonance oxygen image hypoxic fraction plus radiation dose strongly correlates with tumor cure in FSa fibrosarcomas

M Elas, R Bell, D Hleihel, ED Barth, C McFaul… - International Journal of …, 2008 - Elsevier
PURPOSE: Tumor hypoxia has long been known to produce resistance to radiation. In this
study, electron paramagnetic resonance (EPR) oxygen imaging was investigated for its …

EPR oxygen images predict tumor control by a 50% tumor control radiation dose

…, B Butler, C Li, R Wardak, R DeVries, ED Barth… - Cancer research, 2013 - AACR
Clinical trials to ameliorate hypoxia as a strategy to relieve the radiation resistance it causes
have prompted a need to assay the precise extent and location of hypoxia in tumors. …

Diminished Aqueous Microviscosity of Tumors in Murine Models Measured with in Vivo Radiofrequency Electron Paramagnetic Resonance

HJ Halpern, GVR Chandramouli, ED Barth, C Yu… - Cancer research, 1999 - AACR
Using very low frequency in vivo electron paramagnetic resonance (EPR), we have compared,
for the first time, the average microviscosity of the total aqueous compartment of murine …

Comparison of 250 MHz electron spin echo and continuous wave oxygen EPR imaging methods for in vivo applications

B Epel, SV Sundramoorthy, ED Barth, C Mailer… - Medical …, 2011 - Wiley Online Library
Purpose: The authors compare two electron paramagnetic resonance imaging modalities at
250 MHz to determine advantages and disadvantages of those modalities forin vivo oxygen …