Long-term cardiovascular mortality in patients with differentiated thyroid carcinoma: an observational study

EN Klein Hesselink, MS Klein Hesselink… - Journal of Clinical …, 2013 - ascopubs.org
Purpose The primary aim was to study the risk of cardiovascular mortality in patients with
differentiated thyroid carcinoma (DTC). Secondary aims were to evaluate all-cause mortality …

Effects of radioiodine treatment on salivary gland function in patients with differentiated thyroid carcinoma: a prospective study

ENK Hesselink, AH Brouwers, JR de Jong… - Journal of Nuclear …, 2016 - Soc Nuclear Med
Complaints of a dry mouth (xerostomia) and sialoadenitis are frequent side effects of radioiodine
treatment in differentiated thyroid cancer (DTC) patients. However, detailed prospective …

Increased risk of atrial fibrillation after treatment for differentiated thyroid carcinoma

EN Klein Hesselink, JD Lefrandt… - The Journal of …, 2015 - academic.oup.com
Background: Patients with differentiated thyroid carcinoma (DTC) have a favorable prognosis
after treatment with thyroidectomy, radioiodine, and TSH suppression. However, treatment …

Bone Marrow Function After 131I Therapy in Patients With Differentiated Thyroid Carcinoma

HT Prinsen, EN Klein Hesselink… - The Journal of …, 2015 - academic.oup.com
Objective: The primary objective was to evaluate the short- and long-term toxic effects of
radioiodine ( 131 I) therapy on bone marrow function in differentiated thyroid carcinoma (DTC) …

Long-term effects of radioiodine treatment on salivary gland function in adult survivors of pediatric differentiated thyroid carcinoma

T Selvakumar, M Nies, MSK Hesselink… - Journal of Nuclear …, 2019 - Soc Nuclear Med
Pediatric differentiated thyroid cancer (DTC) is a rare disease. Initial treatment of DTC
consists of a total or near-total thyroidectomy and 131 I therapy. Previous studies on adults …

Increased global DNA hypomethylation in distant metastatic and dedifferentiated thyroid cancer

EN Klein Hesselink, C Zafon… - The Journal of …, 2018 - academic.oup.com
Context Global DNA hypomethylation is a major event for the development and progression
of cancer, although the significance in thyroid cancer remains unclear. Therefore, we aimed …

NT-proBNP is increased in differentiated thyroid carcinoma patients and may predict cardiovascular risk

ENK Hesselink, ANA van der Horst-Schrivers… - Clinical …, 2017 - Elsevier
Introduction Chronic suppression of TSH in patients treated for differentiated thyroid
carcinoma (DTC) may induce cardiac damage and increase risk for cardiovascular events and …

[PDF][PDF] Long-term follow-up for differentiated thyroid carcinoma patients: a reconsideration

RAL van der Wardt, ACM Persoon, ENK Hesselink… - Thyroid, 2017 - research.rug.nl
Since recurrence of disease can develop up to 30 years after initial treatment, a long-term
follow-up has been advocated for patients with differentiated thyroid cancer (DTC)(1). A …

[PDF][PDF] Increased global DNA hypomethylation in metastatic and dedifferentiated thyroid cancer

ENK Hesselink, C Zafón, R Buj, N Villalmanzo… - research.rug.nl
Genetic and epigenetic alterations are crucial for the development and progression of cancer.
One of these events is global DNA hypomethylation, of which the significance in thyroid …

Long-term quality of life in adult survivors of pediatric differentiated thyroid carcinoma

M Nies, MS Klein Hesselink… - The Journal of …, 2017 - academic.oup.com
Context: Little is known about long-term quality of life (QoL) of survivors of pediatric differentiated
thyroid carcinoma. Therefore, this study aimed to evaluate generic health-related QoL (…