User profiles for Erin L. Symonds
Erin SymondsSenior medical scientist, Flinders Medical Centre Verified email at sa.gov.au Cited by 2627 |
[HTML][HTML] Advances in fecal occult blood tests: the FIT revolution
GP Young, EL Symonds, JE Allison, SR Cole… - Digestive diseases and …, 2015 - Springer
There is a wide choice of fecal occult blood tests (FOBTs) for colorectal cancer screening.
Goal: To highlight the issues applicable when choosing a FOBT, in particular which FOBT is …
Goal: To highlight the issues applicable when choosing a FOBT, in particular which FOBT is …
[HTML][HTML] Evaluation of an assay for methylated BCAT1 and IKZF1 in plasma for detection of colorectal neoplasia
SK Pedersen, EL Symonds, RT Baker, DH Murray… - BMC cancer, 2015 - Springer
Background Specific genes, such as BCAT1 and IKZF1, are methylated with high frequency
in colorectal cancer (CRC) tissue compared to normal colon tissue specimens. Such DNA …
in colorectal cancer (CRC) tissue compared to normal colon tissue specimens. Such DNA …
[HTML][HTML] The use of circulating tumor DNA to monitor and predict response to treatment in colorectal cancer
…, S Vatandoust, GP Young, EL Symonds - Frontiers in …, 2019 - frontiersin.org
Background: Colorectal cancer is one of the most common cancers worldwide and has a high
mortality rate following disease recurrence. Treatment efficacy is maximized by providing …
mortality rate following disease recurrence. Treatment efficacy is maximized by providing …
Mechanisms of activation of mouse and human enteroendocrine cells by nutrients
EL Symonds, M Peiris, AJ Page, B Chia, H Dogra… - Gut, 2015 - gut.bmj.com
Objective Inhibition of food intake and glucose homeostasis are both promoted when nutrients
stimulate enteroendocrine cells (EEC) to release gut hormones. Several specific nutrient …
stimulate enteroendocrine cells (EEC) to release gut hormones. Several specific nutrient …
A cross‐sectional study comparing a blood test for methylated BCAT1 and IKZF1 tumor‐derived DNA with CEA for detection of recurrent colorectal cancer
…, L Bambacas, P Hollington, EL Symonds - Cancer …, 2016 - Wiley Online Library
Recurrence will develop in 30–50% of colorectal cancer ( CRC ) cases despite apparent
clearance following treatment. Carcinoembryonic antigen ( CEA ) is the only guideline‐…
clearance following treatment. Carcinoembryonic antigen ( CEA ) is the only guideline‐…
A Blood Test for MethylatedBCAT1andIKZF1vs. a Fecal Immunochemical Test for Detection of Colorectal Neoplasia
EL Symonds, SK Pedersen, RT Baker… - clinical and …, 2016 - journals.lww.com
OBJECTIVES: To compare the performance of a new blood test for colorectal cancer (CRC)
to an established fecal immunochemical test (FIT) in a study population with the full range of …
to an established fecal immunochemical test (FIT) in a study population with the full range of …
Factors affecting faecal immunochemical test positive rates: demographic, pathological, behavioural and environmental variables
EL Symonds, JM Osborne, SR Cole… - Journal of Medical …, 2015 - journals.sagepub.com
Objectives Positive rates in faecal immunochemical test (FIT)-based colorectal cancer
screening programmes vary, suggesting that differences between programmes may affect test …
screening programmes vary, suggesting that differences between programmes may affect test …
[HTML][HTML] Circulating tumour DNA for monitoring colorectal cancer—a prospective cohort study to assess relationship to tissue methylation, cancer characteristics and …
EL Symonds, SK Pedersen, DH Murray, M Jedi… - Clinical …, 2018 - Springer
Background Cell-free circulating tumour-derived DNA (ctDNA) can be detected by testing
for methylated BCAT1 and IKZF1 DNA, which has proven sensitivity for colorectal cancer (CRC)…
for methylated BCAT1 and IKZF1 DNA, which has proven sensitivity for colorectal cancer (CRC)…
Relationship between post-surgery detection of methylated circulating tumor DNA with risk of residual disease and recurrence-free survival
DH Murray, EL Symonds, GP Young, S Byrne… - Journal of cancer …, 2018 - Springer
Purpose Methylation in IKZF1 and BCAT1 are common events in colorectal cancer (CRC).
They are often detected in blood as circulating tumor DNA (ctDNA) at diagnosis and …
They are often detected in blood as circulating tumor DNA (ctDNA) at diagnosis and …
Circulating epigenetic biomarkers for detection of recurrent colorectal cancer
EL Symonds, SK Pedersen, D Murray, SE Byrne… - Cancer, 2020 - Wiley Online Library
Background The sensitive detection of recurrent colorectal cancer (CRC) by the measurement
of circulating tumor DNA (ctDNA) might improve the chance of a cure. This study …
of circulating tumor DNA (ctDNA) might improve the chance of a cure. This study …