Nicotine, the addictive chemical in tobacco smoke, initiates its actions in brain through nicotinic
acetylcholine receptors (nAChRs). In particular, nAChRs containing β 2 -subunits (β 2 *-…

Human postmortem studies have reported decreases with age in high affinity nicotine
binding in brain. We investigated the effect of age on β 2 -containing nicotinic acetylcholine …

Tobacco smoking is highly comorbid with heavy alcohol drinking, yet the interaction of tobacco
smoking and alcohol drinking on brain catecholaminergic synaptic markers is unexplored…

Context Adaptations in γ-aminobutyric acid type A (GABA A )–benzodiazepine receptors
contribute to the neurobiology of human alcohol dependence and withdrawal. Objective To …

The study of the effects of sex and hormones on brain chemistry and neurotransmission is of
increasing importance as evidence emerges of sex differences in behavioral symptoms and …

Human postmortem studies have reported decreases with age in high‐affinity nicotine binding
in brain. We have been investigating in vivo the availability of the β 2 ‐containing nicotinic …

Human postmortem studies have reported decreases with age in high-affinity nicotine binding
in brain. We have been investigating in vivo the availability of the ß2-containing nicotinic …

… My brother, Yishai Frohlich, and I share a deep trust and understanding. Always interesting
… my mother, Colette Heitlinger Frohlich, and my father, Henach Frohlich, who raised me to …

Recently, infections with emerging zoonotic bacteria of the genus Bartonella have been
reported in association with a range of central nervous system (CNS) symptoms. Currently, it …

… as evolved signals do—we could thus call them signal innovations (Frohlich and van Schaik,
2020)… higher in the Northwest Sumatran population than the Bornean populations (Frohlich …