Lipoprotein (a) in atherosclerotic cardiovascular disease and aortic stenosis: a European Atherosclerosis Society consensus statement

F Kronenberg, S Mora, ESG Stroes… - European heart …, 2022 - academic.oup.com
This 2022 European Atherosclerosis Society lipoprotein(a) [Lp(a)] consensus statement
updates evidence for the role of Lp(a) in atherosclerotic cardiovascular disease (ASCVD) and …

New risk factors for atherosclerosis and patient risk assessment

JC Fruchart, MC Nierman, ESG Stroes, JJP Kastelein… - Circulation, 2004 - Am Heart Assoc
Advances in our understanding of the ways in which the traditional cardiovascular risk factors,
including standard lipid (eg, total cholesterol, low-density lipoprotein cholesterol, and high-…

The endothelial glycocalyx: a potential barrier between health and vascular disease

…, JBL Hoekstra, JJP Kastelein, ESG Stroes - Current opinion in …, 2005 - journals.lww.com
Cumulating evidence suggests that an intact glycocalyx protects the vessel wall, whereas
disruption of the glycocalyx upon atherogenic stimuli increases vascular vulnerability for …

[HTML][HTML] Simvastatin with or without ezetimibe in familial hypercholesterolemia

JJP Kastelein, F Akdim, ESG Stroes… - … England Journal of …, 2008 - Mass Medical Soc
Background Ezetimibe, a cholesterol-absorption inhibitor, reduces levels of low-density
lipoprotein (LDL) cholesterol when added to statin treatment. However, the effect of ezetimibe on …

Triglyceride-rich lipoproteins and their remnants: metabolic insights, role in atherosclerotic cardiovascular disease, and emerging therapeutic strategies—a consensus …

…, AT Remaley, B Staels, ESG Stroes… - European heart …, 2021 - academic.oup.com
Recent advances in human genetics, together with a large body of epidemiologic, preclinical,
and clinical trial results, provide strong support for a causal association between …

[PDF][PDF] Improvement of insulin sensitivity after lean donor feces in metabolic syndrome is driven by baseline intestinal microbiota composition

…, E Zoetendal, WM de Vos, MJ Serlie, ESG Stroes… - Cell metabolism, 2017 - cell.com
The intestinal microbiota has been implicated in insulin resistance, although evidence
regarding causality in humans is scarce. We therefore studied the effect of lean donor (allogenic) …

Loss of endothelial glycocalyx during acute hyperglycemia coincides with endothelial dysfunction and coagulation activation in vivo

…, JBL Hoekstra, H Vink, JJP Kastelein, ESG Stroes - Diabetes, 2006 - Am Diabetes Assoc
Hyperglycemia is associated with increased susceptibility to atherothrombotic stimuli. The
glycocalyx, a layer of proteoglycans covering the endothelium, is involved in the protective …

Lipoprotein (a), PCSK9 inhibition, and cardiovascular risk: insights from the FOURIER trial

ML O'Donoghue, S Fazio, RP Giugliano, ESG Stroes… - Circulation, 2019 - Am Heart Assoc
Background: Lipoprotein(a) [Lp(a)] may play a causal role in atherosclerosis. PCSK9 (proprotein
convertase subtilisin/kexin 9) inhibitors have been shown to significantly reduce plasma …

High-density lipoprotein cholesterol, high-density lipoprotein particle size, and apolipoprotein AI: significance for cardiovascular risk: the IDEAL and EPIC-Norfolk …

…, ML Larsen, C Lindahl, ESG Stroes… - Journal of the American …, 2008 - jacc.org
Objectives : This study was designed to assess the relationship of high-density-lipoprotein
cholesterol (HDL-C), HDL particle size, and apolipoprotein AI (apoA-I) with the occurrence of …

Efficacy and safety of high-density lipoprotein cholesterol-increasing compounds: a meta-analysis of randomized controlled trials

…, BA Hutten, JJP Kastelein, ESG Stroes - Journal of the American …, 2005 - jacc.org
Objectives : The aim of this research was to estimate the efficacy and safety of current high-density
lipoprotein cholesterol (HDL-C)-increasing drugs. Background : Epidemiologic …