Tumor targeting properties of monoclonal antibodies with different affinity for target antigen CD44V6 in nude mice bearing head‐and‐neck cancer xenografts

…, M Siegmund, E Ostermann, E Patzelt… - … journal of cancer, 2002 - Wiley Online Library
The CD44 protein family consists of isoforms with tissue‐specific expression, which are
encoded by standard exons and up to 9 alternatively spliced variant exons (v2–v10) of the same …

Characterization of a high-affinity monoclonal antibody specific for CD44v6 as candidate for immunotherapy of squamous cell carcinomas

KH Heider, M Sproll, S Susani, E Patzelt… - Cancer Immunology …, 1996 - Springer
Variant isoforms of CD44, a family of cell-surface glycoproteins generated by alternative
splicing and post-translational modifications, are expressed in a variety of human tumors and …

Expression of CD44 splice variants in squamous epithelia and squamous cell carcinomas of the head and neck

…, S SEITER, AI BORN, E PATZELT… - The Journal of …, 1996 - Wiley Online Library
Splice variants of the adhesion molecule CD44 have been described as essential for the
lymphatic spread of rat tumour cells and are claimed to be involved in the metastatic spread of …

Cap-recognizing protein of influenza virus

D Blaas, E Patzelt, E Kuechler - Virology, 1982 - Elsevier
Globin mRNA-primed in vitro transcription of influenza virus is inhibited by m 7 GpppGm, m
7 GpppG, and m 7 GTP indicating that the cap analogs block the specific binding site …

Assembly of pre-mRNA splicing complex is cap dependent

E Patzelt, E Thalmann, K Hartmuth, D Blass… - Nucleic acids …, 1987 - academic.oup.com
To study the influence of the ubiquitous cap structure of nuclear pre-mRNAs on the assembly
of a functional splicing complex, the in vitro splicing of a truncated human metallothionein …

Mapping of Branch Sites in trans-Spliced Pre-mRNAs of Trypanosoma brucei

E Patzelt, KL Perry, N Agabian - Molecular and cellular biology, 1989 - Taylor & Francis
The process of trans splicing is essential to the maturation of all mRNAs in the Trypanosomatidae,
a family of protozoan parasites, and to specific mRNAs in several species of nematode…

[PDF][PDF] Gallium-68 chelate imaging of human colon carcinoma xenografts pretargeted with bispecific anti-CD44V6/anti-gallium chelate antibodies

G Klivenyi, J Schuhmacher, E Patzelt… - Journal of Nuclear …, 1998 - Soc Nuclear Med
Anti-Ga chelate MAbs were raised by immunization of BALB/c mice with Ga-N, N'-[2-hydroxy-5-(ethylene-f3-carboxy)
benzyl] eth Recently, we demonstrated the feasibility of combining …

Development of transferrin-polycation/DNA based vectors for gene delivery to melanoma cells

L Wightman, E Patzelt, E Wagner… - Journal of drug …, 1999 - Taylor & Francis
We describe the comparison of non-viral polycation transfection reagents, adenovirus-enhanced
transferrinfection (AVET), polyethylenimine (PEI800) and transferrin-conjugated PEI800 …

Human interferon ω1: isolation of the gene, expression in Chinese hamster ovary cells and characterization of the recombinant protein

…, I Maurer-Fogy, E Ostermann, E Patzelt… - … et Biophysica Acta (BBA …, 1991 - Elsevier
A gene encoding human interferon ω-1 (IFN-ω1) was isolated from a cosmid library,
sequenced and expressed in Chinese hamster ovary (CHO) cells under the control of an SV40-…

[PDF][PDF] votume 15 Number 4 1987 Nucleic Acids Research

E Patzelt, E Thalmann, K Hartmuth, D Blaas… - Citeseer
To study the influence of the ubiquitous cap structure of nuclear pre-mRNAs on the assembly
of a functional splicing complex, the in v itro splicing of a truncated human metallothlonein …