User profiles for Eric A. Klein
Eric A. KleinChairman, Glickman Urological and Kidney Institute, Cleveland Clinic Verified email at ccf.org Cited by 69985 |
Effect of selenium and vitamin E on risk of prostate cancer and other cancers: the Selenium and Vitamin E Cancer Prevention Trial (SELECT)
SM Lippman, EA Klein, PJ Goodman, MS Lucia… - Jama, 2009 - jamanetwork.com
Context Secondary analyses of 2 randomized controlled trials and supportive epidemiologic
and preclinical data indicated the potential of selenium and vitamin E for preventing …
and preclinical data indicated the potential of selenium and vitamin E for preventing …
Vitamin E and the risk of prostate cancer: the Selenium and Vitamin E Cancer Prevention Trial (SELECT)
EA Klein, IM Thompson, CM Tangen, JJ Crowley… - Jama, 2011 - jamanetwork.com
Context The initial report of the Selenium and Vitamin E Cancer Prevention Trial (SELECT)
found no reduction in risk of prostate cancer with either selenium or vitamin E supplements …
found no reduction in risk of prostate cancer with either selenium or vitamin E supplements …
[HTML][HTML] Sensitive and specific multi-cancer detection and localization using methylation signatures in cell-free DNA
MC Liu, GR Oxnard, EA Klein, C Swanton, MV Seiden… - Annals of …, 2020 - Elsevier
Background Early cancer detection could identify tumors at a time when outcomes are
superior and treatment is less morbid. This prospective case-control sub-study (from …
superior and treatment is less morbid. This prospective case-control sub-study (from …
Task Group 142 report: Quality assurance of medical accelerators a
EE Klein, J Hanley, J Bayouth, FF Yin, W Simon… - Medical …, 2009 - Wiley Online Library
The task group (TG) for quality assurance of medical accelerators was constituted by the
American Association of Physicists in Medicine's Science Council under the direction of the …
American Association of Physicists in Medicine's Science Council under the direction of the …
A contemporary prostate cancer grading system: a validated alternative to the Gleason score
Background Despite revisions in 2005 and 2014, the Gleason prostate cancer (PCa)
grading system still has major deficiencies. Combining of Gleason scores into a three-tiered …
grading system still has major deficiencies. Combining of Gleason scores into a three-tiered …
Tirzepatide versus insulin glargine in type 2 diabetes and increased cardiovascular risk (SURPASS-4): a randomised, open-label, parallel-group, multicentre, phase 3 …
…, L Herandez-Vazquez, SH Hsia, MR Jardula, EJ Klein… - The Lancet, 2021 - thelancet.com
Background We aimed to assess efficacy and safety, with a special focus on cardiovascular
safety, of the novel dual GIP and GLP-1 receptor agonist tirzepatide versus insulin glargine …
safety, of the novel dual GIP and GLP-1 receptor agonist tirzepatide versus insulin glargine …
[HTML][HTML] Predicting the outcome of salvage radiation therapy for recurrent prostate cancer after radical prostatectomy
Purpose An increasing serum prostate-specific antigen (PSA) level is the initial sign of
recurrent prostate cancer among patients treated with radical prostatectomy. Salvage radiation …
recurrent prostate cancer among patients treated with radical prostatectomy. Salvage radiation …
[HTML][HTML] Clinical validation of a targeted methylation-based multi-cancer early detection test using an independent validation set
EA Klein, D Richards, A Cohn, M Tummala… - Annals of …, 2021 - Elsevier
Background A multi-cancer early detection (MCED) test used to complement existing screening
could increase the number of cancers detected through population screening, potentially …
could increase the number of cancers detected through population screening, potentially …
Predicting 15-year prostate cancer specific mortality after radical prostatectomy
Purpose : Long-term prostate cancer specific mortality after radical prostatectomy is poorly
defined in the era of widespread screening. An understanding of the treated natural history of …
defined in the era of widespread screening. An understanding of the treated natural history of …
A 17-gene assay to predict prostate cancer aggressiveness in the context of Gleason grade heterogeneity, tumor multifocality, and biopsy undersampling
Background Prostate tumor heterogeneity and biopsy undersampling pose challenges to
accurate, individualized risk assessment for men with localized disease. Objective To identify …
accurate, individualized risk assessment for men with localized disease. Objective To identify …