High-density lipoproteins suppress chemokines and chemokine receptors in vitro and in vivo
…, DT Beattie, S Nakhla, E Van Der Vorst… - … , and vascular biology, 2010 - Am Heart Assoc
Objective— To investigate whether high-density lipoproteins (HDLs) suppress chemokine (CCL2,
CCL5, and CX 3 CL1) and chemokine receptor (CCR2 and CX 3 CR1) expression, a …
CCL5, and CX 3 CL1) and chemokine receptor (CCR2 and CX 3 CR1) expression, a …
[HTML][HTML] Hematopoietic miR155 deficiency enhances atherosclerosis and decreases plaque stability in hyperlipidemic mice
…, IMJ Wolfs, LJ Stöger, EPC Van Der Vorst… - PloS one, 2012 - journals.plos.org
microRNA-155 (miR155) is a central regulator of immune responses that is induced by
inflammatory mediators. Although miR155 is considered to be a pro-inflammatory microRNA, in …
inflammatory mediators. Although miR155 is considered to be a pro-inflammatory microRNA, in …
Vascular CXCR4 limits atherosclerosis by maintaining arterial integrity: evidence from mouse and human studies
… †Drs van der Vorst and Neideck contributed equally to this … †Drs van der Vorst and Neideck
contributed equally to this … Drs van der Vorst and Megens performed and analyzed the in vivo …
contributed equally to this … Drs van der Vorst and Megens performed and analyzed the in vivo …
Propionate attenuates atherosclerosis by immune-dependent regulation of intestinal cholesterol metabolism
…, R Cineus, AN Hegazy, EPC van der Vorst… - European Heart …, 2022 - academic.oup.com
Aims Atherosclerotic cardiovascular disease (ACVD) is a major cause of mortality and
morbidity worldwide, and increased low-density lipoproteins (LDLs) play a critical role in …
morbidity worldwide, and increased low-density lipoproteins (LDLs) play a critical role in …
[HTML][HTML] Inflammatory chemokines in atherosclerosis
Atherosclerosis is a long-term, chronic inflammatory disease of the vessel wall leading to
the formation of occlusive or rupture-prone lesions in large arteries. Complications of …
the formation of occlusive or rupture-prone lesions in large arteries. Complications of …
Epithelial magnesium transport by TRPM6 is essential for prenatal development and adult survival
…, L Sytik, F Torben, V Jurinovic, EPC van der Vorst… - Elife, 2016 - elifesciences.org
10.7554/eLife.20914.001 Mg 2+ regulates many physiological processes and signalling
pathways. However, little is known about the mechanisms underlying the organismal balance of …
pathways. However, little is known about the mechanisms underlying the organismal balance of …
Imaging the cytokine receptor CXCR4 in atherosclerotic plaques with the radiotracer 68Ga-pentixafor for PET
…, M Mohring, Y Döring, EPC van der Vorst… - Journal of Nuclear …, 2017 - Soc Nuclear Med
68 Ga-pentixafor is a radiotracer for PET that binds with nanomolar affinity to CXCR4. The
CXCR4 receptor is expressed at the surface of inflammatory cells. The objective of the study …
CXCR4 receptor is expressed at the surface of inflammatory cells. The objective of the study …
[HTML][HTML] Chemokines and their receptors in Atherosclerosis
Atherosclerosis, a chronic inflammatory disease of the medium- and large-sized arteries, is
the main underlying cause of cardiovascular diseases (CVDs) most often leading to a …
the main underlying cause of cardiovascular diseases (CVDs) most often leading to a …
High-density lipoproteins and apolipoprotein A1
EPC van der Vorst - … and invertebrate respiratory proteins, lipoproteins and …, 2020 - Springer
High-density Lipoproteins lipoprotein High-Density Lipoproteins (HDL) (HDL) and its
Apolipoprotein A1 main protein Proteins component apolipoprotein (apo)AI, play an important role …
Apolipoprotein A1 main protein Proteins component apolipoprotein (apo)AI, play an important role …
[PDF][PDF] High-density lipoproteins exert pro-inflammatory effects on macrophages via passive cholesterol depletion and PKC-NF-κB/STAT1-IRF1 signaling
EPC van Der Vorst, K Theodorou, Y Wu, MA Hoeksema… - Cell metabolism, 2017 - cell.com
Membrane cholesterol modulates a variety of cell signaling pathways and functions. While
cholesterol depletion by high-density lipoproteins (HDLs) has potent anti-inflammatory effects …
cholesterol depletion by high-density lipoproteins (HDLs) has potent anti-inflammatory effects …