Evaluation of Oatp and Mrp2 activities in hepatobiliary excretion using newly developed positron emission tomography tracer [11C] dehydropravastatin in rats
…, Y Katayama, T Okauchi, E Hayashinaka… - … of Pharmacology and …, 2013 - ASPET
… Tomotaka Shingaki, Tadayuki Takashima, Ryosuke Ijuin, Xuan Zhang, Tomohiro Onoue,
Yumiko Katayama, Takashi Okauchi, Emi Hayashinaka, Yilong Cui, Yasuhiro Wada, Masaaki …
Yumiko Katayama, Takashi Okauchi, Emi Hayashinaka, Yilong Cui, Yasuhiro Wada, Masaaki …
[HTML][HTML] 18F-FIMP: a LAT1-specific PET probe for discrimination between tumor tissue and inflammation
…, A Mawatari, N Shibata, WE Hume, E Hayashinaka… - Scientific reports, 2019 - nature.com
Positron emission tomography (PET) imaging can assist in the early-phase diagnostic and
therapeutic evaluation of tumors. Here, we report the radiosynthesis, small animal PET …
therapeutic evaluation of tumors. Here, we report the radiosynthesis, small animal PET …
Synthesis of 11C-Radiolabeled Eribulin as a Companion Diagnostics PET Tracer for Brain Glioblastoma
…, T Nakaoka, S Irie, E Hayashinaka… - Bulletin of the …, 2023 - academic.oup.com
The successful 11 C-radiolabeling of eribulin, an analog of the marine natural product
halichondrin B, and an approved anticancer drug for the treatment of breast cancer and …
halichondrin B, and an approved anticancer drug for the treatment of breast cancer and …
PET imaging of the gastrointestinal absorption of orally administered drugs in conscious and anesthetized rats
…, M Takahashi, N Suzuki, E Hayashinaka… - Journal of Nuclear …, 2011 - Soc Nuclear Med
This study assessed the process of gastrointestinal drug absorption in vivo using PET. Methods:
18 F-FDG was used as a model probe and was orally administered to rats as a solution. …
18 F-FDG was used as a model probe and was orally administered to rats as a solution. …
Quantitative Evaluation of mMate1 Function Based on Minimally Invasive Measurement of Tissue Concentration Using PET with [11C]Metformin in Mouse
…, Y Katayama, T Okauchi, E Hayashinaka… - Pharmaceutical …, 2015 - Springer
… Emi Hayashinaka … Ewan Hume, Yumiko Katayama, Takashi Okauchi, Emi Hayashinaka,
Yasuhiro Wada, Yilong Cui & Yasuyoshi Watanabe … Emi Hayashinaka …
Yasuhiro Wada, Yilong Cui & Yasuyoshi Watanabe … Emi Hayashinaka …
[18F]DPA-714 PET imaging for the quantitative evaluation of early spatiotemporal changes of neuroinflammation in rat brain following status epilepticus
…, A Igesaka, D Hu, T Nakaoka, E Hayashinaka… - European Journal of …, 2022 - Springer
[18F]DPA-714 PET imaging for the quantitative evaluation of early spatiotemporal changes
of neuroinflammation in rat brain following status epilepticus | European Journal of Nuclear …
of neuroinflammation in rat brain following status epilepticus | European Journal of Nuclear …
Molecular imaging analysis of intestinal insulin absorption boosted by cell-penetrating peptides by using positron emission tomography
…, K Hasegawa, M Nishimura, E Hayashinaka… - Journal of controlled …, 2010 - Elsevier
Molecular imaging technique by use of positron emission tomography (PET) is a noninvasive
tool that allows one to quantitatively analyze the function of endogenous molecules and …
tool that allows one to quantitatively analyze the function of endogenous molecules and …
Dynamic analysis of fluid distribution in the gastrointestinal tract in rats: positron emission tomography imaging after oral administration of nonabsorbable marker,[18F] …
…, T Shingaki, Y Katayama, E Hayashinaka… - Molecular …, 2013 - ACS Publications
To develop potent drugs for oral use, information on their pharmacokinetic (PK) properties
after oral administration is of great importance. We have recently reported the utility of positron …
after oral administration is of great importance. We have recently reported the utility of positron …
The synthesis and biodistribution of [11C] metformin as a PET probe to study hepatobiliary transport mediated by the multi-drug and toxin extrusion transporter 1 …
…, T Okauchi, Y Katayama, E Hayashinaka… - Bioorganic & medicinal …, 2013 - Elsevier
In order to develop a new positron emission tomography (PET) probe to study hepatobiliary
transport mediated by the multi-drug and toxin extrusion transporter 1 (MATE1), 11 C-…
transport mediated by the multi-drug and toxin extrusion transporter 1 (MATE1), 11 C-…
PET imaging analysis with 64Cu in disulfiram treatment for aberrant copper biodistribution in Menkes disease mouse model
…, E Ninomiya, S Kudo, E Hayashinaka… - Journal of Nuclear …, 2014 - Soc Nuclear Med
Menkes disease (MD), an X-linked recessive disorder of copper metabolism caused by
mutations in the copper-transporting ATP7A gene, results in growth failure and severe …
mutations in the copper-transporting ATP7A gene, results in growth failure and severe …