Label retention assays remain the state‐of‐the‐art approach to identify the location of intraorgan
epithelial stem cell niches, in situ and in vivo. They are commonly used in organs with …

A novel α-particle emitting monoclonal antibody construct targeting the external domain of
prostate-specific membrane antigen (PSMA) was prepared and evaluated in vitro and in vivo. …

Inradioimmunotherapy, the emission characteristics of the radioisotope is critical in determining
the radiation dose to the tumor compared to normal organs. If antibodies internalize and …

A33, a monoclonal antibody that targets colon carcinomas, was labeled with 125 I or 131 I
and the relative therapeutic efficacy of the 2 radiolabeled species was compared in a human …

Monoclonal antibody (mAb) A33 reacts with an antigen expressed by > 95% of colon cancer
and normal colon epithelial cells. An earlier Phase I trial of 131 I-labeled mAb A33 ( 131 I-…

External Beam Radiotherapy: Comparative Page 1 range of tumor models, antibodies,
radiolabels and irradia tion procedures, making direct comparisons difficult. RIT was more …

… Barendswaard,MD,Leuke miaService,MemorialSloan-KetteringcancerCenter,1275YorkAve.,New
York,NY10021. … IUT AND XRT XENOGRAFT RESPONSE •Barendswaard … Humm …

Monoclonal antibody (mAb) A33 detects a glycoprotein homogeneously expressed by> 95%
of human colon cancers and by normal colon cells. The A33 antigen is not secreted or shed …

Multiple myeloma (MM) is characterized by the monoclonal expansion of malignant plasma
cells in the bone marrow (BM) and the production of monoclonal protein (M-protein). With the …

… When a liver gets injured and the regenerative capacity of mature hepatocytes and/or
cholangiocytes is impaired, these LPCs become activated in humans as well as in animal models …