ABSTRACT. The relative role of steroids and tacrolimus in the development of glucose
metabolic disorders and hyperlipidemia after renal transplantation has not yet been clearly …

Most studies concerning the influence of tacrolimus on glucose metabolism have been
performed either in animals or after organ transplantation. These clinical studies have largely …

Post-transplant diabetes mellitus (PTDM) is a frequent complication in renal transplantation.
While both tacrolimus and ciclosporin are known to be associated with PTDM, the …

Although there are experimental reports of cytochrome P450 3A4 iso‐enzyme (CYP3A4)
induction by glucocorticoids, there are no clinical reports about an interaction between …

ABSTRACT. The long-term effects of tacrolimus and cyclosporine on pancreatic islet cell
function in renal transplant recipients are unclear. Therefore, a prospective, randomized, …

… Boots JM, Christiaans MH, Van Duijnhoven EM, et al. Early steroid withdrawal in renal
transplantation with tacrolimus dual therapy: A pilot study. Transplantation 2002; 74(12) …

Individual HLA mismatches may differentially impact graft survival after kidney transplantation.
Therefore, there is a need for a reliable tool to define permissible HLA mismatches in …

Background. With tacrolimus-based immunosuppression, it appears safe to withdraw steroids
3 to 6 months after renal transplantation. We hypothesized whether steroids could also be …

The clinical significance of non‐ HLA antibodies on renal allograft survival is a matter of
debate, due to differences in reported results and lack of large‐scale studies incorporating …

Whereas regular allocation avoids unacceptable mismatches on the donor organ, allocation
to highly sensitized patients within the Eurotransplant Acceptable Mismatch ( AM ) program …