[HTML][HTML] Alzheimer's disease CSF biomarkers: clinical indications and rational use
E Niemantsverdriet, S Valckx, M Bjerke… - Acta neurologica …, 2017 - Springer
This review focusses on the validation and standardization of Alzheimer’s disease (AD)
cerebrospinal fluid (CSF) biomarkers, as well as on the current clinical indications and rational …
cerebrospinal fluid (CSF) biomarkers, as well as on the current clinical indications and rational …
Association between repeat sizes and clinical and pathological characteristics in carriers of C9ORF72 repeat expansions (Xpansize-72): a cross-sectional cohort …
…, M DeJesus-Hernandez, E Niemantsverdriet… - The Lancet …, 2013 - thelancet.com
Background Hexanucleotide repeat expansions in chromosome 9 open reading frame 72 (C9ORF72)
are the most common known genetic cause of frontotemporal dementia (FTD) and …
are the most common known genetic cause of frontotemporal dementia (FTD) and …
[HTML][HTML] Consensus guidelines for lumbar puncture in patients with neurological diseases
S Engelborghs, E Niemantsverdriet, H Struyfs… - Alzheimer's & Dementia …, 2017 - Elsevier
Introduction Cerebrospinal fluid collection by lumbar puncture (LP) is performed in the diagnostic
workup of several neurological brain diseases. Reluctance to perform the procedure is …
workup of several neurological brain diseases. Reluctance to perform the procedure is …
Intervention with methotrexate in patients with arthralgia at risk of rheumatoid arthritis to reduce the development of persistent arthritis and its disease burden (TREAT …
…, TWJ Huizinga, CF Allaart, E Niemantsverdriet… - The Lancet, 2022 - thelancet.com
Background Rheumatoid arthritis is the most common autoimmune disease worldwide and
requires long-term treatment to suppress inflammation. Currently, treatment is started when …
requires long-term treatment to suppress inflammation. Currently, treatment is started when …
[HTML][HTML] Association of short-term cognitive decline and MCI-to-AD dementia conversion with CSF, MRI, amyloid-and 18F-FDG-PET imaging
J Ottoy, E Niemantsverdriet, J Verhaeghe… - NeuroImage: Clinical, 2019 - Elsevier
Disease-modifying treatment trials are increasingly advanced to the prodromal or preclinical
phase of Alzheimer's disease (AD), and inclusion criteria are based on biomarkers rather …
phase of Alzheimer's disease (AD), and inclusion criteria are based on biomarkers rather …
[HTML][HTML] The cerebrospinal fluid Aβ 1–42/Aβ 1–40 ratio improves concordance with amyloid-PET for diagnosing Alzheimer's disease in a clinical setting
E Niemantsverdriet, J Ottoy, C Somers… - Journal of …, 2017 - content.iospress.com
Background: Evidence suggests that the concordance between amyloid-PET and cerebrospinal
fluid (CSF) amyloid-ß (Aß) increases when the CSF Aß1–42/Aß1–40 ratio is used as …
fluid (CSF) amyloid-ß (Aß) increases when the CSF Aß1–42/Aß1–40 ratio is used as …
[HTML][HTML] Enhanced treatment strategies and distinct disease outcomes among autoantibody-positive and-negative rheumatoid arthritis patients over 25 years: a …
XME Matthijssen, E Niemantsverdriet… - PLoS …, 2020 - journals.plos.org
Background Based on different genetic and environmental risk factors and histology, it has
been proposed that rheumatoid arthritis (RA) consists of 2 types: autoantibody-positive and …
been proposed that rheumatoid arthritis (RA) consists of 2 types: autoantibody-positive and …
Associating Alzheimer's disease pathology with its cerebrospinal fluid biomarkers
…, A Sieben, A Rozemuller, E Niemantsverdriet… - Brain, 2022 - academic.oup.com
Alzheimer’s disease CSF biomarkers 42 amino acid long amyloid-β peptide (Aβ 1–42 ),
total tau protein (T-tau), and tau protein phosphorylated at threonine 181 (P-tau 181 ) are …
total tau protein (T-tau), and tau protein phosphorylated at threonine 181 (P-tau 181 ) are …
[HTML][HTML] Genome-wide association study of Alzheimer's disease CSF biomarkers in the EMIF-AD Multimodal Biomarker Discovery dataset
…, CE Teunissen, E Niemantsverdriet… - Translational …, 2020 - nature.com
Alzheimer’s disease (AD) is the most prevalent neurodegenerative disorder and the most
common form of dementia in the elderly. Susceptibility to AD is considerably determined by …
common form of dementia in the elderly. Susceptibility to AD is considerably determined by …
[PDF][PDF] Imaging detected tenosynovitis of metacarpophalangeal and wrist joints: an increasingly recognised characteristic of rheumatoid arthritis
E Niemantsverdriet… - Clin Exp …, 2018 - clinexprheumatol.org
Tenosynovitis is traditionally recognised at physical examination in patients with inflammatory
rheumatic diseases, such as, eg psoriatic arthritis and (longstanding) rheumatoid arthritis (…
rheumatic diseases, such as, eg psoriatic arthritis and (longstanding) rheumatoid arthritis (…