A flow cytometric (FCM) assay has been developed for the determination of cell-mediated
cytotoxicity (CMC). In the assay, the target tumour cell population was labelled with a …

Using flow cytometry (FCM), an assay has been developed for the determination of antibody-dependent
cell-mediated cytotoxicity (ADCC). Target cells were labelled with a membrane …

OBJECTIVE: The primary focus of the current report was to determine if there was an association
between LSC-R and ASI-Lite scores in cocaine-dependent individuals. The secondary …

Rates of cigarette smoking are 3- to 4-fold greater among those with cocaine-dependence,
and compared to non-users, cocaine users are at greater risk of incurring smoking-related …

Recent evidence suggests that interactions between endothelial selectins and tumor surface
selectin ligands may be of importance in cancer metastasis. To investigate the role of such …

Objective To examine normal and psoriatic skin and synovial tissue from patients with psoriatic
arthritis (PsA) for evidence of monocyte chemotactic protein-1 (MCP-1) mediated T cell …

Carcinoembryonic antigen (CEA) is highly expressed by most tumours of gastrointestinal
origin, but its use as a target for tumour therapy is complicated by the high levels of soluble …

Current cocaine treatments may be enhanced with a better understanding of the underlying
mechanisms that contribute to the onset and maintenance of the disease, such as life stress …

Monoclonal antibodies (mAbs) have been used to treat malignancies in humans with varying
degrees of success. Progress has been hindered by the lack of suitable animal models, …

In this study, a human carcinoembryonic antigen (CEA) transgenic (CEA.Tg) mouse model
was evaluated for the preclinical assessment of agents directed against CEA. Methods: Cell-…