User profiles for Edwin C. Pratt
 | Edwin C PrattMemorial Sloan Kettering Cancer Center Verified email at mskcc.org Cited by 875 |
FDA-approved ferumoxytol displays anti-leukaemia efficacy against cells with low ferroportin levels
…, EC Pratt, H Zong, A Lara-Martinez, C Kaittanis… - Nature …, 2019 - nature.com
Acute myeloid leukaemia is a fatal disease for most patients. We have found that ferumoxytol
(Feraheme), an FDA-approved iron oxide nanoparticle for iron deficiency treatment, …
(Feraheme), an FDA-approved iron oxide nanoparticle for iron deficiency treatment, …
Simultaneous quantitative imaging of two PET radiotracers via the detection of positron–electron annihilation and prompt gamma emissions
In conventional positron emission tomography (PET), only one radiotracer can be imaged at
a time, because all PET isotopes produce the same two 511 keV annihilation photons. Here …
a time, because all PET isotopes produce the same two 511 keV annihilation photons. Here …
Utilizing the power of Cerenkov light with nanotechnology
The characteristic blue glow of Cerenkov luminescence (CL) arises from the interaction
between a charged particle travelling faster than the phase velocity of light and a dielectric …
between a charged particle travelling faster than the phase velocity of light and a dielectric …
MISER chromatography (multiple injections in a single experimental run): the chromatogram is the graph
An experimental approach for rapid analysis and convenient interpretation of multiparallel
experiments is described. Conventional approaches use a series of individual …
experiments is described. Conventional approaches use a series of individual …
Prospective testing of clinical Cerenkov luminescence imaging against standard-of-care nuclear imaging for tumour location
In oncology, the feasibility of Cerenkov luminescence imaging (CLI) has been assessed by
imaging superficial lymph nodes in a few patients undergoing diagnostic 18 F-fluoro-2-…
imaging superficial lymph nodes in a few patients undergoing diagnostic 18 F-fluoro-2-…
Nanoparticles as multimodal photon transducers of ionizing radiation
In biomedical imaging, nanoparticles combined with radionuclides that generate Cerenkov
luminescence are used in diagnostic imaging, photon-induced therapies and as activatable …
luminescence are used in diagnostic imaging, photon-induced therapies and as activatable …
Nanoparticles and radiotracers: advances toward radionanomedicine
In this study, we cover the convergence of radiochemistry for imaging and therapy with advances
in nanoparticle ( NP ) design for biomedical applications. We first explore NP properties …
in nanoparticle ( NP ) design for biomedical applications. We first explore NP properties …
Ultrasmall downconverting nanoparticle for enhanced Cerenkov imaging
Cerenkov imaging provides an opportunity to expand the application of approved radiotracers
and therapeutic agents by utilizing them for optical approaches, which opens new …
and therapeutic agents by utilizing them for optical approaches, which opens new …
Innovations in nuclear imaging instrumentation: Cerenkov imaging
Cerenkov luminescence (CL) is blue glow light produced by charged subatomic particles
travelling faster than the phase velocity of light in a dielectric medium such as water or tissue. …
travelling faster than the phase velocity of light in a dielectric medium such as water or tissue. …
Ambient Light Resistant Shortwave Infrared Fluorescence Imaging for Preclinical Tumor Delineation via the pH Low-Insertion Peptide Conjugated to Indocyanine …
Shortwave infrared (900–1,700 nm) fluorescence imaging (SWIRFI) has shown significant
advantages over visible (400–650 nm) and near-infrared (700–900 nm) fluorescence imaging …
advantages over visible (400–650 nm) and near-infrared (700–900 nm) fluorescence imaging …