Background— Cardiac transthyretin (ATTR) amyloidosis is a progressive and fatal
cardiomyopathy for which several promising therapies are in development. The diagnosis is …

Publisher Summary This chapter presents methods generally applicable to the preparation
of native collagen from a variety of sources. The preparation of a collagen sample generally …

Understanding cellular response to environmental stress has broad implications for human
disease. AMP-activated protein kinase (AMPK) orchestrates the regulation of energy-…

The strength, resorption rate, and biocompatibility of collagenous biomaterials are profoundly
influenced by the method and extent of crosslinking. We compared the effects of two …

Cardiac amyloidosis is a form of restrictive infiltrative cardiomyopathy that confers significant
mortality. Due to the relative rarity of cardiac amyloidosis, clinical and diagnostic expertise …

Background Sarcoidosis is a systemic disease characterized by significant clinical heterogeneity.
Although most frequently involving the lungs, sarcoidosis may affect any organ. The …

Clones of embryonic chick chondrocytes have been isolated and collagen biosynthesis has
been followed as the clones grow and eventually lose division capacity. Analysis of collagen …

Importance Transthyretin cardiac amyloidosis (also known as ATTR cardiac amyloidosis) is
an increasingly recognized cause of heart failure with preserved ejection fraction. In single-…

Isolation and chromatography of collagen from chick cartilage revealed an excess of α1
relative to α2-chains. Characterization of the cyanogen bromide peptides from the α1 fraction …

Objectives : The study evaluated the automatic prediction of obstructive disease from myocardial
perfusion imaging (MPI) by deep learning as compared with total perfusion deficit (TPD)…