Molecular and cellular effects of radiotherapy on tumor microenvironment (TME) can help
prime and propagate antitumor immunity. We hypothesized that delivering radiation to all …

The aggregate-induced limitation for high power-conversion efficiencies (PCEs) of perylene-diimide
(PDI):polymer solar cells can be circumvented when two simple rules are respected; …

Rationale: Clinical interest in combining targeted radionuclide therapies (TRT) with
immunotherapies is growing. External beam radiation therapy (EBRT) activates a type 1 interferon (…

Nuclear medicine leverages different types of radiometals for disease diagnosis and
treatment, but these applications usually require them to be stably chelated. Given the often-…

Theranostic nanoparticles hold the potential to greatly improve cancer management by
providing personalized medicine. Although many theranostic nanoconstructs have been …

The therapeutic efficacy of photodynamic therapy is limited by the ability of light to penetrate
tissues. Due to this limitation, Cerenkov luminescence (CL) from radionuclides has recently …

We report the first targeted nuclear medicine application of the lanthanum radionuclides 132/135
La. These isotopes represent a matched pair for diagnosis via the positron emissions of …

Recent advances in molecular characterization of tumors have made possible the emergence
of new types of cancer therapies where traditional cytotoxic drugs and nonspecific …

Finding improved therapeutic strategies against T-cell Non-Hodgkin’s Lymphoma (NHL)
remains an unmet clinical need. We implemented a theranostic approach employing a tumor-…

43Sc and 44gSc are both positron-emitting radioisotopes of scandium with suitable half-lives
and favorable positron energies for clinical positron emission tomography (PET) imaging. …