Inhibiting metastasis and preventing tumor relapse by triggering host immunity with tumor-targeted photodynamic therapy using photosensitizer-loaded functional …

X Yu, D Gao, L Gao, J Lai, C Zhang, Y Zhao, L Zhong… - ACS …, 2017 - ACS Publications
Effective cancer therapy depends not only on destroying the primary tumor but also on
conditioning the host immune system to recognize and eliminate residual tumor cells and prevent …

[HTML][HTML] Enhanced anti-tumor efficacy through a combination of integrin αvβ6-targeted photodynamic therapy and immune checkpoint inhibition

L Gao, C Zhang, D Gao, H Liu, X Yu, J Lai, F Wang… - Theranostics, 2016 - ncbi.nlm.nih.gov
“Training” the host immune system to recognize and systemically eliminate residual tumor
lesions and micrometastases is a promising strategy for cancer therapy. In this study, we …

Inhibition of tumor growth and metastasis by photoimmunotherapy targeting tumor-associated macrophage in a sorafenib-resistant tumor model

C Zhang, L Gao, Y Cai, H Liu, D Gao, J Lai, B Jia… - Biomaterials, 2016 - Elsevier
Tumor-associated macrophages (TAMs) play essential roles in tumor invasion and
metastasis, and contribute to drug resistance. Clinical evidence suggests that TAM levels are …

[HTML][HTML] Molecular imaging of tumor-infiltrating macrophages in a preclinical mouse model of breast cancer

X Sun, D Gao, L Gao, C Zhang, X Yu, B Jia, F Wang… - Theranostics, 2015 - ncbi.nlm.nih.gov
Significant evidence has indicated that tumor-associated macrophages (TAMs) play a
critical role in the proliferation, invasion, angiogenesis, and metastasis of a variety of human …

Inhibitory effect and mechanism of various fruit extracts on the formation of heterocyclic aromatic amines and flavor changes in roast large yellow croaker …

M Li, S Lin, R Wang, D Gao, Z Bao, D Chen, Y Tang… - Food Control, 2022 - Elsevier
The large yellow croaker (Pseudosciaena crocea) is one of the most commercially important
marine fish in China and is a fixture at Chinese tables. Herein, we determined the formation …

[HTML][HTML] Radiomics nomogram analyses for differentiating pneumonia and acute paraquat lung injury

W Yanling, G Duo, G Zuojun, S Zhongqiang… - Scientific reports, 2019 - nature.com
Paraquat poisoning has become a serious public health problem in some Asian countries
because of misuse or suicide. We sought to develop and validate a radiomics nomogram …

[HTML][HTML] Plasma metabolic profiling reveals that chromium yeast alleviates the negative effects of heat stress in mid-lactation dairy cows

Y Wo, F Ma, Q Shan, D Gao, Y Jin, P Sun - Animal Nutrition, 2023 - Elsevier
Chromium yeast (CY) supplementation has the potential to alleviate the negative effects of
heat stress in dairy cows, but the mechanism remains elusive. We aimed to identify the …

A near-infrared phthalocyanine dye-labeled agent for integrin αvβ6-targeted theranostics of pancreatic cancer

D Gao, L Gao, C Zhang, H Liu, B Jia, Z Zhu, F Wang… - Biomaterials, 2015 - Elsevier
Integrin αvβ6 is widely upregulated in variant malignant cancers but is undetectable in
normal organs, making it a promising target for cancer diagnostic imaging and therapy. Using …

Antimicrobial susceptibility and molecular characterization of macrolide resistance of Mycoplasma bovis isolates from multiple provinces in China

LC Kong, D Gao, BY Jia, Z Wang, YH Gao… - Journal of Veterinary …, 2016 - jstage.jst.go.jp
Mycoplasma bovis has spread widely throughout the world via animal movement and has
become an important pathogen of bovine respiratory disease. However, the minimum …

The destructive mechanism of Aβ 1–42 protofibrils by norepinephrine revealed via molecular dynamics simulations

D Gao, J Wan, Y Zou, Y Gong, X Dong, Z Xu… - Physical Chemistry …, 2022 - pubs.rsc.org
Amyloid-β (Aβ) fibrillary plaques represent the main hallmarks of Alzheimer's disease (AD),
in addition to tau neurofibrillary tangles. Disrupting early-formed Aβ protofibrils is considered …