Multicriteria VMAT optimization

D Craft, D McQuaid, J Wala, W Chen, E Salari… - Medical …, 2012 - Wiley Online Library
Purpose: To make the planning of volumetric modulated arc therapy (VMAT) faster and to
explore the tradeoffs between planning objectives and delivery efficiency. Methods: A convex …

[HTML][HTML] Daily adaptive radiotherapy for patients with prostate cancer using a high field MR-linac: Initial clinical experiences and assessment of delivered doses …

…, T Herbert, R Lawes, H McNair, D McQuaid… - Clinical and translational …, 2020 - Elsevier
Introduction MR-guided adapted radiotherapy (MRgART) using a high field MR-linac has
recently become available. We report the estimated delivered fractional dose of the first five …

[HTML][HTML] Comparison of CT number calibration techniques for CBCT-based dose calculation

A Dunlop, D McQuaid, S Nill, J Murray… - Strahlentherapie und …, 2015 - ncbi.nlm.nih.gov
Purpose The aim of this work was to compare and validate various computed tomography (CT)
number calibration techniques with respect to cone beam CT (CBCT) dose calculation …

Dosimetric explanations of fatigue in head and neck radiotherapy: an analysis from the PARSPORT Phase III trial

SL Gulliford, AB Miah, S Brennan, D McQuaid… - Radiotherapy and …, 2012 - Elsevier
BACKGROUND: An unexpected finding from the phase III parotid sparing radiotherapy trial,
PARSPORT (ISRCTN48243537, CRUK/03/005), was a statistically significant increase in …

The predictive value of early assessment after 1 cycle of induction chemotherapy with 18F-FDG PET/CT and diffusion-weighted MRI for response to radical …

KH Wong, R Panek, L Welsh, D Mcquaid… - Journal of Nuclear …, 2016 - Soc Nuclear Med
The objective of this study was to assess the predictive value of early assessment (after 1
cycle of induction chemotherapy [IC]) with 18 F-FDG PET/CT and diffusion-weighted (DW) MRI …

[HTML][HTML] Changes in multimodality functional imaging parameters early during chemoradiation predict treatment response in patients with locally advanced head and …

KH Wong, R Panek, A Dunlop, D Mcquaid… - European journal of …, 2018 - Springer
Objective To assess the optimal timing and predictive value of early intra-treatment changes
in multimodality functional and molecular imaging (FMI) parameters as biomarkers for …

Noninvasive imaging of cycling hypoxia in head and neck cancer using intrinsic susceptibility MRI

…, AM Riddell, DM Koh, A Dunlop, D Mcquaid… - Clinical Cancer …, 2017 - AACR
Purpose: To evaluate intrinsic susceptibility (IS) MRI for the identification of cycling hypoxia,
and the assessment of its extent and spatial distribution, in head and neck squamous cell …

[HTML][HTML] MRI-based assessment of 3D intrafractional motion of head and neck cancer for radiation therapy

OJ Gurney-Champion, D McQuaid, A Dunlop… - International Journal of …, 2018 - Elsevier
Purpose To determine the 3-dimensional (3D) intrafractional motion of head and neck
squamous cell carcinoma (HNSCC). Methods and Materials Dynamic contrast-enhanced …

[HTML][HTML] Online adaptive radiotherapy for head and neck cancers on the MR linear accelerator: Introducing a novel modified adapt-to-shape approach

A Gupta, A Dunlop, A Mitchell, D McQuaid, S Nill… - Clinical and translational …, 2022 - Elsevier
Introduction The Elekta Unity MR-Linac (MRL) has enabled adaptive radiotherapy (ART) for
patients with head and neck cancers (HNC). Adapt-To-Shape-Lite (ATS-Lite) is a novel …

Repeatability and sensitivity of measurements in patients with head and neck squamous cell carcinoma at 3T

…, MA Schmidt, S Doran, D Mcquaid… - Journal of Magnetic …, 2016 - Wiley Online Library
Purpose To determine whether quantitation of is sufficiently repeatable and sensitive to
detect clinically relevant oxygenation levels in head and neck squamous cell carcinoma (HNSCC…