Everyone knows and seems to agree that melanocytes are there to generate melanin – an
intriguing, but underestimated multipurpose molecule that is capable of doing far more than …

The role of the kidney in the pathogenesis of hyperten-sion has long been established,
although recent studies challenge renal hegemony and suggest an important role for vascular …

Overexpressed extracellular matrix (ECM) in pancreatic ductal adenocarcinoma (PDAC)
limits drug penetration into the tumor and is associated with poor prognosis. Here, we …

18 F-PSMA-1007 is a novel prostate-specific membrane antigen (PSMA)–based
radiopharmaceutical for imaging prostate cancer (PCa). The aim of this study was to compare the …

Synthetic cells, artificial cell‐like particles, capable of autonomously synthesizing RNA and
proteins based on a DNA template, are emerging platforms for studying cellular functions and …

Personalized medicine promises to revolutionize cancer therapy by matching the most
effective treatment to the individual patient. Using a nanoparticle-based system, we predict the …

Somatic/clonal evolution is the process of sequential acquisition of vertically transmittable
genetic/epigenetic elements in multicellular organisms. Cancer is the result of somatic …

Monoclonal antibodies (mAbs) hold promise in treating Parkinson's disease (PD), although
poor delivery to the brain hinders their therapeutic application. In the current study, it is …

68 Ga-labeled prostate-specific membrane antigen (PSMA), a PET tracer that was recently
introduced for the imaging of prostate cancer, may accumulate in other solid tumors, including …

While chemotherapy strongly restricts or reverses tumor growth, the response of host tissue
to therapy can counteract its anti-tumor activity by promoting tumor re-growth and/or …