Overview of results of peptide receptor radionuclide therapy with 3 radiolabeled somatostatin analogs

DJ Kwekkeboom, J Mueller-Brand… - Journal of Nuclear …, 2005 - Soc Nuclear Med
A new treatment modality for inoperable or metastasized gastroenteropancreatic tumors is
the use of radiolabeled somatostatin analogs. Initial studies with high doses of [ 111 In-…

Somatostatin receptor-based imaging and therapy of gastroenteropancreatic neuroendocrine tumors

DJ Kwekkeboom, BL Kam, M Van Essen… - Endocrine-related …, 2010 - erc.bioscientifica.com
Somatostatin receptor imaging (SRI) with [111In-DTPA0] octreotide has proven its role in
the diagnosis and staging of gastroenteropancreatic neuroendocrine tumors (GEPNETs). …

Recommendations for management of patients with neuroendocrine liver metastases

…, S Breitenstein, R Salem, D Kwekkeboom… - The lancet …, 2014 - thelancet.com
Many management strategies exist for neuroendocrine liver metastases. These strategies
range from surgery to ablation with various interventional radiology procedures, and include …

[PDF][PDF] Treatment With the Radiolabeled Somatostatin Analog [177Lu-DOTA0,Tyr3]Octreotate: Toxicity, Efficacy, and Survival

DJ Kwekkeboom, WW de Herder, BL Kam… - Journal of Clinical …, 2008 - researchgate.net
Purpose Despite the fact that most gastroenteropancreatic neuroendocrine tumors (GEPNETs)
are slowgrowing, median overall survival (OS) in patients with liver metastases is 2 to 4 …

[HTML][HTML] The joint IAEA, EANM, and SNMMI practical guidance on peptide receptor radionuclide therapy (PRRNT) in neuroendocrine tumours

…, JR Howe, M Cremonesi, DJ Kwekkeboom - European journal of …, 2013 - Springer
Peptide receptor radionuclide therapy (PRRNT) is a molecularly targeted radiation therapy
involving the systemic administration of a radiolabelled peptide designed to target with high …

Radiolabeled Somatostatin Analog [177Lu-DOTA0,Tyr3]Octreotate in Patients With Endocrine Gastroenteropancreatic Tumors

DJ Kwekkeboom, JJ Teunissen, WH Bakker… - Journal of Clinical …, 2005 - ascopubs.org
Purpose There are few treatment options for patients with metastasized or inoperable endocrine
gastroenteropancreatic (GEP) tumors. Chemotherapy can be effective, but the response …

[HTML][HTML] Phase 3 Trial of 177Lu-Dotatate for Midgut Neuroendocrine Tumors

…, P Ruszniewski, D Kwekkeboom… - … England Journal of …, 2017 - Mass Medical Soc
Background Patients with advanced midgut neuroendocrine tumors who have had disease
progression during first-line somatostatin analogue therapy have limited therapeutic options. …

[177Lu-DOTA0,Tyr3]octreotate: comparison with [111In-DTPA0]octreotide in patients

DJ Kwekkeboom, WH Bakker, PP Kooij… - European journal of …, 2001 - Springer
The somatostatin analogue [DOTA 0 ,Tyr 3 ]octreotate has a nine-fold higher affinity for the
somatostatin receptor subtype 2 as compared with [DOTA 0 ,Tyr 3 ]octreotide. Also, labelled …

ENETS consensus guidelines update for the management of patients with functional pancreatic neuroendocrine tumors and non-functional pancreatic neuroendocrine …

…, M Caplin, B Kos-Kudla, D Kwekkeboom… - …, 2016 - karger.com
Only advances that occurred from 2011 to 2014 that either strengthen the previous 2011
guidelines [1, 2] or lead to changes or additional guidelines are reviewed here. Advances and …

ENETS consensus guidelines for the management of patients with gastroduodenal neoplasms

G Delle Fave, DJ Kwekkeboom, E Van Cutsem… - …, 2012 - karger.com
Gianfranco Delle Fave a Dik J. Kwekkeboom b Erik Van Cutsem c Guido Rindi d Beata Kos-Kudla
e Ulrich Knigge f Hironobu Sasano g Paola Tomassetti h Ramon Salazar i Philippe …