[HTML][HTML] Peptide-based drug-delivery systems in biotechnological applications: recent advances and perspectives

D Tesauro, A Accardo, C Diaferia, V Milano, J Guillon… - Molecules, 2019 - mdpi.com
Peptides of natural and synthetic sources are compounds operating in a wide range of
biological interactions. They play a key role in biotechnological applications as both therapeutic …

Supramolecular aggregates containing lipophilic Gd (III) complexes as contrast agents in MRI

A Accardo, D Tesauro, L Aloj, C Pedone… - Coordination Chemistry …, 2009 - Elsevier
Magnetic resonance imaging (MRI) contrast agents based on paramagnetic gadolinium
complexes are widely used in biomedical research and diagnosis. Their application is intended …

Receptor binding peptides for target-selective delivery of nanoparticles encapsulated drugs

…, L Aloj, M Aurilio, G Morelli, D Tesauro - International journal of …, 2014 - Taylor & Francis
Active targeting by means of drug encapsulated nanoparticles decorated with targeting
bioactive moieties represents the next frontier in drug delivery; it reduces drug side effects and …

[HTML][HTML] Peptide-based targeting strategies for simultaneous imaging and therapy with nanovectors

A Accardo, D Tesauro, G Morelli - Polymer journal, 2013 - nature.com
Over recent years, multifunctional compounds that combine diagnostic and therapeutic
modalities using one unified material have been developed and designated as theranostics. …

In vitro and in vivo evaluation of 111In-DTPAGlu-G-CCK8 for cholecystokinin-B receptor imaging

…, A Zannetti, S Del Vecchio, D Tesauro… - Journal of Nuclear …, 2004 - Soc Nuclear Med
Regulatory peptides and their analogs are being extensively investigated as radiopharmaceuticals
for cancer imaging and therapy. Receptors of the cholecystokinin family have been …

Comparison of the binding and internalization properties of 12 DOTA-coupled and 111In-labelled CCK2/gastrin receptor binding peptides: a collaborative project …

…, M Aurilio, V Rinaldi, L D'ambrosio, D Tesauro… - European journal of …, 2011 - Springer
Purpose Specific overexpression of cholecystokinin 2 (CCK2)/gastrin receptors has been
demonstrated in several tumours of neuroendocrine origin. In some of these cancer types, …

[HTML][HTML] Structure–Activity Relationships in NHC–Silver Complexes as Antimicrobial Agents

L Ronga, M Varcamonti, D Tesauro - Molecules, 2023 - mdpi.com
Silver has a long history of antimicrobial activity and received an increasing interest in last
decades owing to the rise in antimicrobial resistance. The major drawback is the limited …

Peptide-modified liposomes for selective targeting of bombesin receptors overexpressed by cancer cells: a potential theranostic agent

…, A Parisi, F Maione, C Cicala, D Tesauro… - International Journal …, 2012 - Taylor & Francis
Objectives Drug delivery systems consisting of liposomes displaying a cell surface receptor-targeting
peptide are being developed to specifically deliver chemotherapeutic drugs to …

Physicochemical properties of mixed micellar aggregates containing CCK peptides and Gd complexes designed as tumor specific contrast agents in MRI

A Accardo, D Tesauro, P Roscigno… - Journal of the …, 2004 - ACS Publications
New amphiphilic molecules containing a bioactive peptide or a claw moiety have been
prepared in order to obtain mixed micelles as target-specific contrast agents in magnetic …

[HTML][HTML] Silver (I) N-Heterocyclic Carbene Complexes: A Winning and Broad Spectrum of Antimicrobial Properties

…, L Ronga, M Varcamonti, D Tesauro - International Journal of …, 2021 - mdpi.com
The evolution of antibacterial resistance has arisen as the main downside in fighting bacterial
infections pushing researchers to develop novel, more potent and multimodal alternative …