User profiles for Detlev Boison
Detlev BoisonDept. of Neurosurgery, Rutgers Robert Wood Johnson Medical School Verified email at rutgers.edu Cited by 16230 |
[HTML][HTML] A ketogenic diet suppresses seizures in mice through adenosine A1 receptors
…, JD Geiger, E Aronica, D Boison - The Journal of …, 2011 - Am Soc Clin Investig
Many individuals with epilepsy benefit from consuming a ketogenic diet, which is similar to
the more commonly known Atkins diet. The underlying molecular reason for this has not been …
the more commonly known Atkins diet. The underlying molecular reason for this has not been …
[HTML][HTML] Adenosine signaling and function in glial cells
D Boison, JF Chen, BB Fredholm - Cell Death & Differentiation, 2010 - nature.com
Despite major advances in a variety of neuroscientific research fields, the majority of
neurodegenerative and neurological diseases are poorly controlled by currently available drugs, …
neurodegenerative and neurological diseases are poorly controlled by currently available drugs, …
Adenosine kinase, epilepsy and stroke: mechanisms and therapies
D Boison - Trends in pharmacological sciences, 2006 - cell.com
Adenosine is an inhibitory modulator of brain activity with neuroprotective and anticonvulsant
properties. Adenosine levels are regulated mainly by adenosine kinase (ADK), an enzyme …
properties. Adenosine levels are regulated mainly by adenosine kinase (ADK), an enzyme …
[HTML][HTML] Epigenetic changes induced by adenosine augmentation therapy prevent epileptogenesis
Epigenetic modifications, including changes in DNA methylation, lead to altered gene
expression and thus may underlie epileptogenesis via induction of permanent changes in …
expression and thus may underlie epileptogenesis via induction of permanent changes in …
Adenosine kinase: exploitation for therapeutic gain
D Boison - Pharmacological reviews, 2013 - ASPET
Adenosine kinase (ADK; EC 2.7.1.20) is an evolutionarily conserved phosphotransferase
that converts the purine ribonucleoside adenosine into 5′-adenosine-monophosphate. This …
that converts the purine ribonucleoside adenosine into 5′-adenosine-monophosphate. This …
The concise guide to pharmacology 2019/20: Enzymes
…, A Beuve, D Boison… - British Journal of …, 2019 - Wiley Online Library
The Concise Guide to PHARMACOLOGY 2019/20 is the fourth in this series of biennial
publications. The Concise Guide provides concise overviews of the key properties of nearly 1800 …
publications. The Concise Guide provides concise overviews of the key properties of nearly 1800 …
New insights into the mechanisms of the ketogenic diet
D Boison - Current opinion in neurology, 2017 - journals.lww.com
… Correspondence to Detlev Boison, PhD, Robert Stone Dow Neurobiology Laboratories,
Legacy Research Institute, 1225 NE 2nd Ave, Portland, OR 97232, USA. Tel: +1 503 413 …
Legacy Research Institute, 1225 NE 2nd Ave, Portland, OR 97232, USA. Tel: +1 503 413 …
The concise guide to pharmacology 2021/22: Enzymes
The Concise Guide to PHARMACOLOGY 2021/22 is the fifth in this series of biennial
publications. The Concise Guide provides concise overviews, mostly in tabular format, of the key …
publications. The Concise Guide provides concise overviews, mostly in tabular format, of the key …
Arousal effect of caffeine depends on adenosine A2A receptors in the shell of the nucleus accumbens
Caffeine, the most widely used psychoactive compound, is an adenosine receptor antagonist.
It promotes wakefulness by blocking adenosine A 2A receptors (A 2A Rs) in the brain, but …
It promotes wakefulness by blocking adenosine A 2A receptors (A 2A Rs) in the brain, but …
Commonalities in epileptogenic processes from different acute brain insults: Do they translate?
The most common forms of acquired epilepsies arise following acute brain insults such as
traumatic brain injury, stroke, or central nervous system infections. Treatment is effective for …
traumatic brain injury, stroke, or central nervous system infections. Treatment is effective for …