Tumor reinitiating cancer stem-like cells are responsible for cancer recurrence associated
with conventional chemotherapy. We developed a doxorubicin-encapsulated polymeric …

… Zynger, Kiril Trpkov; The 2019 Genitourinary Pathology Society (GUPS) White Paper on
Contemporary Grading of Prostate Cancer. Arch Pathol Lab Med 1 April 2021; 145 (4): 461–493…

Purpose: To evaluate the capability of amide proton transfer (APT) MR imaging for detection
of prostate cancer that typically shows a higher tumor cell proliferation rate and cellular …

Glypican 3 (GPC3), a membrane-bound heparin sulfate proteoglycan, may play a role in
promoting embryonic cell growth and differentiation. GPC3 is mutated in Simpson-Golabi-…

The enhancer pioneer transcription factor FoxA1 is a global mediator of steroid receptor (SR)
action in hormone-dependent cancers. In castration-resistant prostate cancer (CRPC), …

Human transcription factors recognize specific DNA sequence motifs to regulate transcription.
It is unknown whether a single transcription factor is able to bind to distinctly different …

Cancer stem-like cells (CSCs) are rare subpopulations of cancer cells that are reported to
be responsible for cancer resistance and metastasis associated with conventional cancer …

Rationale and Objectives To compare prostate morphology, image quality, and diagnostic
performance of 1.5-T endorectal coil magnetic resonance (MR) imaging (MRI) and 3.0-T …

Germ cell tumors (GCTs), rare malignancies that occur in a wide range of locations and
display variable histologic patterns, may pose diagnostic challenges. Glypican 3 (GPC3), a …

In metastatic breast cancer (MBC), it can be difficult to establish the origin if the primary tumor
is triple negative or if there is a loss of biomarker expression. SOX10 expression has been …