Immune checkpoint inhibitor (ICI) treatments benefit some patients with metastatic cancers,
but predictive biomarkers are needed. Findings in selected cancer types suggest that tumor …

The American Society of Clinical Oncology (ASCO) previously published evidencebased
guidelines for the treatment of unresectable non–small-cell lung cancer (NSCLC)[1]. ASCO …

Background PD-1 and PD-L1 inhibitors are active in metastatic urothelial carcinoma, but
positive randomised data supporting their use as a first-line treatment are lacking. In this study …

Purpose Cetuximab is a chimeric monoclonal antibody that targets the epidermal growth
factor receptor. Cetuximab has activity in squamous cell carcinoma and enhances both …

Treatment is complex for patients with head and neck (H&N) cancers with specific site of
disease, stage, and pathologic findings guiding treatment decision-making. Treatment planning …

The NCCN Guidelines for Head and Neck Cancers address tumors arising in the oral cavity
(including mucosal lip), pharynx, larynx, and paranasal sinuses. Occult primary cancer, …

OBJECTIVE: To determine indications for the use of postmastectomy radiotherapy (PMRT)
for patients with invasive breast cancer with involved axil-lary lymph nodes or locally …

The purpose of this article is to provide updated recommendations for the treatment of
patients with stage IV non–small-cell lung cancer. A literature search identified relevant …

BACKGROUND Angiosarcomas are rare tumors. Based on a complete response observed
in a patient with angiosarcoma of the scalp treated with paclitaxel in a Phase II trial, the …

THE GOAL OF ANTIEMETIC therapy is to prevent nausea and vomiting completely. This goal
is achieved for many patients receiving chemotherapy or radiation therapy, and is based …