Background: Several behaviors, besides psychoactive substance ingestion, produce short-term
reward that may engender persistent behavior, despite knowledge of adverse …

Background Synthetic cannabinoids (SC) are a heterogeneous group of compounds developed
to probe the endogenous cannabinoid system or as potential therapeutics. Clandestine …

Background SR141716, a recently developed CB1 cannabinoid receptor antagonist, blocks
acute effects of Δ-9-tetrahydrocannabinol (THC) and other CB1 cannabinoid agonists in …

Background Alcohol withdrawal delirium is the most serious manifestation of alcohol withdrawal.
Evidence suggests that appropriate care improves mortality, but systematic reviews are …

The endogenous opioid system has been recently implicated in the reinforcing actions of
cocaine and other addictive drugs. In this study we examined μ opioid receptor binding in ten …

Background Effects of cannabis, the most commonly encountered non-alcohol drug in
driving under the influence cases, are heavily debated. We aim to determine how blood Δ 9 -…

Objective. —To assess the prevalence of psychoactive substance use disorders (PSUDs)
among a large, unselected group of seriously injured trauma center patients, using a …

Transcranial magnetic stimulation (TMS) is a noninvasive method of brain stimulation used
to treat a variety of neuropsychiatric disorders, but is still in the early stages of study as …

BACKGROUND Δ 9 -Tetrahydrocannabinol (THC) is the most frequently observed illicit
drug in investigations of accidents and driving under the influence of drugs. THC-glucuronide …

This study investigates the clinical significance of a cannabis withdrawal syndrome in 104
adult, non‐treatment‐seeking, primarily cannabis users who reported at least one serious …