Atherosclerosis and its consequences remain the main cause of mortality in industrialized and
developing nations. Plaque burden and progression have been shown to be independent …

Fibrosis is the common endpoint and currently the best predictor of progression of chronic
kidney diseases (CKDs). Despite several drawbacks, biopsies remain the only available …

Background: Molecular magnetic resonance imaging is a promising modality for the
characterization of abdominal aortic aneurysms (AAAs). The combination of different molecular …

Background— The incidence of abdominal aortic aneurysms (AAAs) has increased during
the last decades. However, there is still controversy about the management of medium-sized …

Background— To prospectively evaluate an elastin-specific MR contrast agent (ESMA) for
in vivo targeting of elastic fibers in myocardial infarction (MI) and postinfarction scar …

90 Y-TA138 is a 90 Y-labeled nonpeptide integrin α v β 3 receptor antagonist that binds with
high affinity and specificity to integrin α v β 3 receptors overexpressed on both endothelial …

Purpose To compare delayed-enhancement (DE) magnetic resonance (MR) imaging with an
elastin-specific contrast agent and unenhanced black-blood (BB) MR imaging with regard …

Objective The aim of this study was to demonstrate the feasibility of high-resolution 3-dimensional
aortic vessel wall imaging using a novel elastin-specific magnetic resonance contrast …

Molecular MRI is a promising in-vivo modality to detect and quantify morphological and
molecular vessel-wall changes in atherosclerosis. The combination of different molecular …

Background— Ascending aortic dissection and rupture remain a life-threatening complication
in patients with Marfan syndrome. The extracellular matrix provides strength and elastic …