[HTML][HTML] Quantification, improvement, and harmonization of small lesion detection with state-of-the-art PET

CS van der Vos, D Koopman, S Rijnsdorp… - European journal of …, 2017 - Springer
In recent years, there have been multiple advances in positron emission tomography/computed
tomography (PET/CT) that improve cancer imaging. The present generation of PET/CT …

Performance of digital PET compared with high-resolution conventional PET in patients with cancer

D Koopman, JA van Dalen, H Stevens… - Journal of Nuclear …, 2020 - Soc Nuclear Med
Recently introduced PET systems using silicon photomultipliers with digital readout (dPET)
have an improved timing and spatial resolution, aiming at a better image quality than …

Improving the detection of small lesions using a state-of-the-art time-of-flight PET/CT system and small-voxel reconstructions

D Koopman, JA van Dalen… - Journal of nuclear …, 2015 - Soc Nuclear Med
A major disadvantage of 18 F-FDG PET involves poor detection of small lesions and lesions
with low metabolism, caused by limited spatial resolution and relatively large image voxel …

[HTML][HTML] how to determine the FDG activity for tumour PET imaging that satisfies European guidelines

D Koopman, JAC van Osch, PL Jager, CJA Tenbergen… - EJNMMI physics, 2016 - Springer
Background For tumour imaging with PET, the literature proposes to administer a patient-specific
FDG activity that depends quadratically on a patient’s body weight. However, a …

[HTML][HTML] SUV variability in EARL-accredited conventional and digital PET

D Koopman, PL Jager, CH Slump, S Knollema… - EJNMMI research, 2019 - Springer
Background A high SUV-reproducibility is crucial when different PET scanners are in use. We
evaluated the SUV variability in whole-body FDG-PET scans of patients with suspected or …

Performance of digital PET/CT compared with conventional PET/CT in oncologic patients: a prospective comparison study

TL de Jong, D Koopman, JA van Dalen… - Annals of Nuclear …, 2022 - Springer
Purpose Digital PET systems (dPET) improve lesion detectability as compared to PET
systems with conventional photomultiplier tubes (cPET). We prospectively studied the …

Added value of digital FDG-PET/CT in disease staging and restaging in patients with resectable or borderline resectable pancreatic cancer

TL de Jong, D Koopman, CAJ van der Worp… - Surgical Oncology, 2023 - Elsevier
Background We studied the added value of digital FDG-PET/CT in disease staging and
restaging compared to the standard work-up with contrast enhanced CT (ceCT) and CA19-9 in …

[HTML][HTML] Multicentre quantitative 68Ga PET/CT performance harmonisation

DMV Huizing, D Koopman, JA van Dalen, M Gotthardt… - EJNMMI physics, 2019 - Springer
Purpose Performance standards for quantitative 18 F-FDG PET/CT studies are provided by
the EANM Research Ltd. (EARL) to enable comparability of quantitative PET in multicentre …

[HTML][HTML] Digital PET compliance to EARL accreditation specifications

D Koopman, M Groot Koerkamp, PL Jager, H Arkies… - EJNMMI physics, 2017 - Springer
Background Our aim was to evaluate if a recently introduced TOF PET system with digital
photon counting technology (Philips Healthcare), potentially providing an improved image …

[HTML][HTML] Diagnostic implications of a small-voxel reconstruction for loco-regional lymph node characterization in breast cancer patients using FDG-PET/CT

D Koopman, JA van Dalen, H Arkies, AHJ Oostdijk… - EJNMMI research, 2018 - Springer
Background We evaluated the diagnostic implications of a small-voxel reconstruction for
lymph node characterization in breast cancer patients, using state-of-the-art FDG-PET/CT. We …