Efficient [18F]AlF Radiolabeling of ZHER3:8698 Affibody Molecule for Imaging of HER3 Positive Tumors

…, L Allott, CD Martins, A Vardon, DM Ciobota… - Bioconjugate …, 2016 - ACS Publications
The human epidermal growth factor receptor 3 (HER3) is overexpressed in several cancers,
being linked to a more resistant phenotype and hence leading to poor patient prognosis. …

Near-infrared dual bioluminescence imaging in mouse models of cancer using infraluciferin

…, H Allan, M Vinci, G Kramer-Marek, DM Ciobota… - Elife, 2019 - elifesciences.org
10.7554/eLife.45801.001 Bioluminescence imaging (BLI) is ubiquitous in scientific research
for the sensitive tracking of biological processes in small animal models. However, due to …

Affibody-based PET imaging to guide EGFR-targeted cancer therapy in head and neck squamous cell cancer models

…, C Da Pieve, CD Martins, DM Ciobota… - Journal of Nuclear …, 2019 - Soc Nuclear Med
In head and neck squamous cell cancer, the human epidermal growth factor receptor 1 (EGFR)
is the dominant signaling molecule among all members of the family. So far, cetuximab is …

HER3-mediated resistance to Hsp90 inhibition detected in breast cancer xenografts by affibody-based PET imaging

…, C Da Pieve, TA Burley, R Smith, DM Ciobota… - Clinical Cancer …, 2018 - AACR
Purpose: Recent studies have highlighted a role of HER3 in HER2-driven cancers (eg,
breast cancer), implicating the upregulation of the receptor in resistance to HER-targeted …

[HTML][HTML] Pediatric and adult glioblastoma radiosensitization induced by PI3K/mTOR inhibition causes early metabolic alterations detected by nuclear magnetic …

A Agliano, G Balarajah, DM Ciobota, J Sidhu… - Oncotarget, 2017 - ncbi.nlm.nih.gov
Poor outcome for patients with glioblastomas is often associated with radioresistance. PI3K/mTOR
pathway deregulation has been correlated with radioresistance; therefore, PI3K/…

[HTML][HTML] Radiosynthesis of the anticancer nucleoside analogue Trifluridine using an automated 18 F-trifluoromethylation procedure

A King, A Doepner, D Turton, DM Ciobota… - Organic & …, 2018 - pubs.rsc.org
Trifluoromethyl groups are widespread in medicinal chemistry, yet there are limited 18F-radiochemistry
techniques available for the production of the complementary PET agents. Herein…

Inhibition of the PI3K/mTOR pathway potentiates irradiation effects in paediatric glioblastoma inducing metabolic alterations detected by MRS.

A Agliano, G Balaragah, DM Ciobota, F Raynaud… - Cancer Research, 2013 - AACR
Although radiotherapy is used to treat more than 50% of all cancer patients, in glioblastomas
the percentage of success is limited due to the radioresistance of glioma cells. Reports …

Proceedings of the International Conference European Union's History, Culture and Citizenship, 2021

…, CE CIOBOTA, SD IONITA-BURDA, I Daniela… - 2022 - papers.ssrn.com
The International Conference European Union’s History, Culture and Citizenship was
founded in 2008 and it is dedicated to the academic teachers and researchers, lawyers, …

[HTML][HTML] Exploratory monitoring of the quality and authenticity of commercial honey in Ecuador

L Salvador, M Guijarro, D Rubio, B Aucatoma, T Guillén… - Foods, 2019 - mdpi.com
Honey is one of the oldest sweetening foods and has economic importance, making this
product attractive to adulteration with cheap sugars. This can cause a critical problem in the …

[PDF][PDF] PREMATURITY–A RISK FACTOR FOR CEREBRAL PALSY

…, C Daniela, A Rusmir, A Huditeanu, M Aniko - REVISTA SOCIETĂŢII … - jurnalulpediatrului.ro
The progress made in neonatal medicine led to a better survival rate of premature newborns
of smaller and smaller gestational ages, which also led to a greater risk of complications …