Circulating microRNAs as stable blood-based markers for cancer detection

…, KC O'Briant, A Allen, DW Lin… - Proceedings of the …, 2008 - National Acad Sciences
Improved approaches for the detection of common epithelial malignancies are urgently
needed to reduce the worldwide morbidity and mortality caused by cancer. MicroRNAs (miRNAs) …

[HTML][HTML] Predicting the outcome of salvage radiation therapy for recurrent prostate cancer after radical prostatectomy

…, JM Michalski, HM Sandler, DW Lin… - Journal of clinical …, 2007 - ncbi.nlm.nih.gov
Purpose An increasing serum prostate-specific antigen (PSA) level is the initial sign of
recurrent prostate cancer among patients treated with radical prostatectomy. Salvage radiation …

Association analyses of more than 140,000 men identify 63 new prostate cancer susceptibility loci

…, KL Penney, M Stampfer, JY Park, TA Sellers, HY Lin… - Nature …, 2018 - nature.com
Genome-wide association studies (GWAS) and fine-mapping efforts to date have identified
more than 100 prostate cancer (PrCa)-susceptibility loci. We meta-analyzed genotype data …

Intraprostatic androgens and androgen-regulated gene expression persist after testosterone suppression: therapeutic implications for castration-resistant prostate …

EA Mostaghel, ST Page, DW Lin, L Fazli, IM Coleman… - Cancer research, 2007 - AACR
Androgen deprivation therapy (ADT) remains the primary treatment for advanced prostate
cancer. The efficacy of ADT has not been rigorously evaluated by demonstrating suppression …

Updates in the eighth edition of the tumor-node-metastasis staging classification for urologic cancers

…, WM Stadler, DE Hansel, R Montironi, DW Lin… - European urology, 2018 - Elsevier
The Tumor-Node-Metastasis (TNM) classification on cancer staging, jointly developed by
the American Joint Commission on Cancer (AJCC) and the Union for International Cancer …

A multi-institutional prospective trial in the USA confirms that the 4Kscore accurately identifies men with high-grade prostate cancer

…, L Karsh, EB Krisch, TD Langford, DW Lin… - European urology, 2015 - Elsevier
Background The 4Kscore combines measurement of four kallikreins in blood with clinical
information as a measure of the probability of significant (Gleason ≥7) prostate cancer (PCa) …

Clinically localized prostate cancer: AUA/ASTRO guideline, part I: introduction, risk assessment, staging, and risk-based management

…, EM Horwitz, CJ Kane, E Kirkby, DW Lin… - Journal of …, 2022 - journals.lww.com
Purpose: The summary presented herein represents Part I of the three-part series dedicated
to Clinically Localized Prostate Cancer: AUA/ASTRO Guideline, discussing risk assessment, …

Prostate cancer–major changes in the American Joint Committee on Cancer eighth edition cancer staging manual

…, MB Amin, MW Kattan, DW Lin - CA: a cancer journal …, 2017 - Wiley Online Library
Answer questions and earn CME/CNE The eighth edition of the American Joint Committee
on Cancer (AJCC) tumor‐node‐metastasis (TNM) Staging Manual has been updated and …

Implementation of germline testing for prostate cancer: Philadelphia Prostate Cancer Consensus Conference 2019

…, B O'Neil, W Pinover, P Pinto, W Poage… - Journal of Clinical …, 2020 - ascopubs.org
PURPOSE Germline testing (GT) is a central feature of prostate cancer (PCA) treatment,
management, and hereditary cancer assessment. Critical needs include optimized multigene …

Post-transcriptional generation of miRNA variants by multiple nucleotidyl transferases contributes to miRNA transcriptome complexity

…, EC Knouf, RK Parkin, BR Fritz, DW Lin… - Genome …, 2011 - genome.cshlp.org
Modification of microRNA sequences by the 3′ addition of nucleotides to generate so-called
“isomiRs” adds to the complexity of miRNA function, with recent reports showing that 3′ …