User profiles for Daniel Stover
Daniel G. StoverOhio State University Comprehensive Cancer Center Verified email at osumc.edu Cited by 9118 |
[HTML][HTML] Scalable whole-exome sequencing of cell-free DNA reveals high concordance with metastatic tumors
Whole-exome sequencing of cell-free DNA (cfDNA) could enable comprehensive profiling
of tumors from blood but the genome-wide concordance between cfDNA and tumor biopsies …
of tumors from blood but the genome-wide concordance between cfDNA and tumor biopsies …
[PDF][PDF] Genomic and transcriptomic landscape of triple-negative breast cancers: subtypes and treatment strategies
We comprehensively analyzed clinical, genomic, and transcriptomic data of a cohort of 465
primary triple-negative breast cancer (TNBC). PIK3CA mutations and copy-number gains of …
primary triple-negative breast cancer (TNBC). PIK3CA mutations and copy-number gains of …
Response and resistance to BET bromodomain inhibitors in triple-negative breast cancer
Triple-negative breast cancer (TNBC) is a heterogeneous and clinically aggressive disease
for which there is no targeted therapy 1 , 2 , 3 . BET bromodomain inhibitors, which have …
for which there is no targeted therapy 1 , 2 , 3 . BET bromodomain inhibitors, which have …
[HTML][HTML] CDK7-dependent transcriptional addiction in triple-negative breast cancer
Triple-negative breast cancer (TNBC) is a highly aggressive form of breast cancer that
exhibits extremely high levels of genetic complexity and yet a relatively uniform transcriptional …
exhibits extremely high levels of genetic complexity and yet a relatively uniform transcriptional …
Integrin-β4 identifies cancer stem cell-enriched populations of partially mesenchymal carcinoma cells
Neoplastic cells within individual carcinomas often exhibit considerable phenotypic heterogeneity
in their epithelial versus mesenchymal-like cell states. Because carcinoma cells with …
in their epithelial versus mesenchymal-like cell states. Because carcinoma cells with …
A global Fine‐Root Ecology Database to address below‐ground challenges in plant ecology
Variation and tradeoffs within and among plant traits are increasingly being harnessed by
empiricists and modelers to understand and predict ecosystem processes under changing …
empiricists and modelers to understand and predict ecosystem processes under changing …
[HTML][HTML] Molecular subtyping and genomic profiling expand precision medicine in refractory metastatic triple-negative breast cancer: the FUTURE trial
…, J Ding, X Zhu, J Zou, C Verschraegen, DG Stover… - Cell research, 2021 - nature.com
Triple-negative breast cancer (TNBC) is a highly heterogeneous disease, and molecular
subtyping may result in improved diagnostic precision and targeted therapies. Our previous …
subtyping may result in improved diagnostic precision and targeted therapies. Our previous …
[PDF][PDF] CDK12 inhibition reverses de novo and acquired PARP inhibitor resistance in BRCA wild-type and mutated models of triple-negative breast cancer
Although poly(ADP-ribose) polymerase (PARP) inhibitors are active in homologous recombination
(HR)-deficient cancers, their utility is limited by acquired resistance after restoration of …
(HR)-deficient cancers, their utility is limited by acquired resistance after restoration of …
[PDF][PDF] Cancer cells co-opt the neuronal redox-sensing channel TRPA1 to promote oxidative-stress tolerance
Cancer cell survival is dependent on oxidative-stress defenses against reactive oxygen species
(ROS) that accumulate during tumorigenesis. Here, we show a non-canonical oxidative-…
(ROS) that accumulate during tumorigenesis. Here, we show a non-canonical oxidative-…
[HTML][HTML] Association of cell-free DNA tumor fraction and somatic copy number alterations with survival in metastatic triple-negative breast cancer
Purpose Cell-free DNA (cfDNA) offers the potential for minimally invasive genome-wide profiling
of tumor alterations without tumor biopsy and may be associated with patient prognosis. …
of tumor alterations without tumor biopsy and may be associated with patient prognosis. …