User profiles for Daniel Stover

Daniel G. Stover

Ohio State University Comprehensive Cancer Center
Verified email at osumc.edu
Cited by 9118

[HTML][HTML] Scalable whole-exome sequencing of cell-free DNA reveals high concordance with metastatic tumors

…, G Ha, SS Freeman, AD Choudhury, DG Stover… - Nature …, 2017 - nature.com
Whole-exome sequencing of cell-free DNA (cfDNA) could enable comprehensive profiling
of tumors from blood but the genome-wide concordance between cfDNA and tumor biopsies …

[PDF][PDF] Genomic and transcriptomic landscape of triple-negative breast cancers: subtypes and treatment strategies

…, YX Ren, YX Zhao, YS Yang, Z Niu, ZG Cao, DG Stover… - Cancer cell, 2019 - cell.com
We comprehensively analyzed clinical, genomic, and transcriptomic data of a cohort of 465
primary triple-negative breast cancer (TNBC). PIK3CA mutations and copy-number gains of …

Response and resistance to BET bromodomain inhibitors in triple-negative breast cancer

…, J Ryan, E Doherty, H Mohammed, H Guo, DG Stover… - Nature, 2016 - nature.com
Triple-negative breast cancer (TNBC) is a heterogeneous and clinically aggressive disease
for which there is no targeted therapy 1 , 2 , 3 . BET bromodomain inhibitors, which have …

[HTML][HTML] CDK7-dependent transcriptional addiction in triple-negative breast cancer

…, S Xie, H Yuzugullu, T Von, H Li, Z Lin, DG Stover… - Cell, 2015 - cell.com
Triple-negative breast cancer (TNBC) is a highly aggressive form of breast cancer that
exhibits extremely high levels of genetic complexity and yet a relatively uniform transcriptional …

Integrin-β4 identifies cancer stem cell-enriched populations of partially mesenchymal carcinoma cells

…, SE Pierce, C Kroeger, DG Stover… - Proceedings of the …, 2017 - National Acad Sciences
Neoplastic cells within individual carcinomas often exhibit considerable phenotypic heterogeneity
in their epithelial versus mesenchymal-like cell states. Because carcinoma cells with …

A global Fine‐Root Ecology Database to address below‐ground challenges in plant ecology

…, GT Freschet, J Kattge, C Roumet, DB Stover… - New …, 2017 - Wiley Online Library
Variation and tradeoffs within and among plant traits are increasingly being harnessed by
empiricists and modelers to understand and predict ecosystem processes under changing …

[HTML][HTML] Molecular subtyping and genomic profiling expand precision medicine in refractory metastatic triple-negative breast cancer: the FUTURE trial

…, J Ding, X Zhu, J Zou, C Verschraegen, DG Stover… - Cell research, 2021 - nature.com
Triple-negative breast cancer (TNBC) is a highly heterogeneous disease, and molecular
subtyping may result in improved diagnostic precision and targeted therapies. Our previous …

[PDF][PDF] CDK12 inhibition reverses de novo and acquired PARP inhibitor resistance in BRCA wild-type and mutated models of triple-negative breast cancer

…, C Cruz, AK Greifenberg, S Dust, DG Stover… - Cell reports, 2016 - cell.com
Although poly(ADP-ribose) polymerase (PARP) inhibitors are active in homologous recombination
(HR)-deficient cancers, their utility is limited by acquired resistance after restoration of …

[PDF][PDF] Cancer cells co-opt the neuronal redox-sensing channel TRPA1 to promote oxidative-stress tolerance

N Takahashi, HY Chen, IS Harris, DG Stover… - Cancer cell, 2018 - cell.com
Cancer cell survival is dependent on oxidative-stress defenses against reactive oxygen species
(ROS) that accumulate during tumorigenesis. Here, we show a non-canonical oxidative-…

[HTML][HTML] Association of cell-free DNA tumor fraction and somatic copy number alterations with survival in metastatic triple-negative breast cancer

DG Stover, HA Parsons, G Ha… - Journal of Clinical …, 2018 - ncbi.nlm.nih.gov
Purpose Cell-free DNA (cfDNA) offers the potential for minimally invasive genome-wide profiling
of tumor alterations without tumor biopsy and may be associated with patient prognosis. …