User profiles for Daniel Holt

Daniel Holt

- Verified email at jhmi.edu - Cited by 14474

Daniel T. Holt

- Verified email at louisville.edu - Cited by 8946

Readiness for organizational change: The systematic development of a scale

DT Holt, AA Armenakis, HS Feild… - The Journal of applied …, 2007 - journals.sagepub.com
Using a systematic item-development framework as a guide (ie, item development, questionnaire
administration, item reduction, scale evaluation, and replication), this article discusses …

Imaging brain amyloid in Alzheimer's disease with Pittsburgh Compound‐B

…, Y Wang, G Blomqvist, DP Holt… - Annals of Neurology …, 2004 - Wiley Online Library
This report describes the first human study of a novel amyloid‐imaging positron emission
tomography (PET) tracer, termed Pittsburgh Compound‐B (PIB), in 16 patients with diagnosed …

Synthesis and Evaluation of 11C-Labeled 6-Substituted 2-Arylbenzothiazoles as Amyloid Imaging Agents

CA Mathis, Y Wang, DP Holt, GF Huang… - Journal of medicinal …, 2003 - ACS Publications
The synthesis and evaluation of a series of neutral analogues of thioflavin-T (termed BTA's)
with high affinities for aggregated amyloid and a wide range of lipophilicities are reported. …

PET imaging of serotonin 1A receptor binding in depression

WC Drevets, E Frank, JC Price, DJ Kupfer, D Holt… - Biological …, 1999 - Elsevier
Background: The serotonin-1A (5HT1A) receptor system has been implicated in the
pathophysiology of major depression by postmortem studies of suicide victims and depressed …

Kinetic modeling of amyloid binding in humans using PET imaging and Pittsburgh Compound-B

…, X Lu, JA Hoge, SK Ziolko, DP Holt… - Journal of Cerebral …, 2005 - journals.sagepub.com
A valid quantitative imaging method for the measurement of amyloid deposition in humans
could improve Alzheimer's disease (AD) diagnosis and antiamyloid therapy assessment. Our …

Uncharged thioflavin-T derivatives bind to amyloid-beta protein with high affinity and readily enter the brain

WE Klunk, Y Wang, G Huang, ML Debnath, DP Holt… - Life sciences, 2001 - Elsevier
In vivo assessment of the beta-sheet proteins deposited in amyloid plaques (Aβ peptide) or
neurofibrillary tangles (tau protein) presents a target for the development of biological …

Organizational justice and individuals' withdrawal: Unlocking the influence of emotional exhaustion

…, JB Bernerth, F Walter, DT Holt - Journal of management …, 2010 - Wiley Online Library
This study examined the relationships between organizational justice and withdrawal
outcomes and whether emotional exhaustion was a mediator of these linkages. Data were …

A lipophilic thioflavin-T derivative for positron emission tomography (PET) imaging of amyloid in brain

…, ME McLellan, MP Frosch, BT Hyman, DP Holt… - Bioorganic & medicinal …, 2002 - Elsevier
The synthesis of a new lipophilic thioflavin-T analogue (2-[4′-(methylamino)phenyl]benzothiazole,
6) with high affinity for amyloid is reported. Intravenous injection of [ 11 C]-labeled 6 …

Examining the link between “familiness” and performance: Can the F–PEC untangle the family business theory jungle?

…, DF Kuratko, DT Holt - … theory and practice, 2008 - journals.sagepub.com
Family business research appears to be caught in a “jungle” of competing theories in regards
to familiness and performance. This study provides a further empirical examination into …

Viewing family firm behavior and governance through the lens of agency and stewardship theories

K Madison, DT Holt, FW Kellermanns… - Family Business …, 2016 - journals.sagepub.com
Agency and stewardship theories are prominent perspectives to examine myriad issues within
family firms. Although considered opposing theories, both address the same phenomena: …