Poly (ADP-ribose) polymerase-deficient mice are protected from streptozotocin-induced diabetes

…, DJ Brat, DK Krug, CC Watkins… - Proceedings of the …, 1999 - National Acad Sciences
Streptozotocin (STZ) selectively destroys insulin-producing beta islet cells of the pancreas
providing a model of type I diabetes. Poly(ADP-ribose) polymerase (PARP) is a nuclear …

[HTML][HTML] Insulin restores neuronal nitric oxide synthase expression and function that is lost in diabetic gastropathy

CC Watkins, A Sawa, S Jaffrey… - The Journal of …, 2000 - Am Soc Clin Investig
Gastrointestinal dysfunction is common in diabetic patients. In genetic (nonobese diabetic)
and toxin-elicited (streptozotocin) models of diabetes in mice, we demonstrate defects in …

Cognitive impairment in patients with AIDS–prevalence and severity

CC Watkins, GJ Treisman - HIV/AIDS-Research and Palliative Care, 2015 - Taylor & Francis
The advent of highly active antiretroviral therapy has prolonged the life expectancy of HIV
patients and decreased the number of adults who progress to AIDS and HIV-associated …

Initial evaluation of 11C-DPA-713, a novel TSPO PET ligand, in humans

…, O Uzuner, DA Hammoud, CC Watkins… - Journal of Nuclear …, 2009 - Soc Nuclear Med
Translocator protein (TSPO) is upregulated in activated microglia and thus can serve as a
marker of neuroinflammation. Recently, a novel radioligand, 11 C-N,N-diethyl-2-[2-(4-…

Regional brain distribution of translocator protein using [11C]DPA-713 PET in individuals infected with HIV

…, R Rais, C Rojas, JL McGlothan, CC Watkins… - Journal of …, 2014 - Springer
Imaging the brain distribution of translocator protein (TSPO), a putative biomarker for glial
cell activation and neuroinflammation, may inform management of individuals infected with …

Clinical studies of neuroinflammatory mechanisms in schizophrenia

CC Watkins, SR Andrews - Schizophrenia research, 2016 - Elsevier
Watkins contributed to the conception and design, interpretation of data, drafting and
revising the article and funding for the project. Dr. Andrews contributed to the data collection, …

A novel neuron-enriched homolog of the erythrocyte membrane cytoskeletal protein 4.1

…, S Blackshaw, D Liao, CC Watkins… - Journal of …, 1999 - Soc Neuroscience
We report the molecular cloning and characterization of 4.1N, a novel neuronal homolog of
the erythrocyte membrane cytoskeletal protein 4.1 (4.1R). The 879 amino acid protein shares …

Inhibition of glutamate carboxypeptidase II (GCPII) activity as a treatment for cognitive impairment in multiple sclerosis

KA Rahn, CC Watkins, J Alt, R Rais… - Proceedings of the …, 2012 - National Acad Sciences
Half of all patients with multiple sclerosis (MS) experience cognitive impairment, for which
there is no pharmacological treatment. Using magnetic resonance spectroscopy (MRS), we …

[HTML][HTML] Neuropsychiatric complications of aging with HIV

CC Watkins, GJ Treisman - Journal of neurovirology, 2012 - Springer
Persons over age 50 are not only aging with human immunodeficiency virus (HIV) infection
but also represent a high proportion of new HIV infections. Neuropsychiatric symptoms, …

[PDF][PDF] Differences in coping among African American women with breast cancer and triple-negative breast cancer.

CC Watkins, IK Kanu, JB Hamilton… - Oncology nursing …, 2017 - academia.edu
Purpose/Objectives: To determine differences in psychological distress, symptoms, coping
capacity, and coping abilities among African American (AA) women with triple-negative breast …