Importance Amyloid-β positron emission tomography (PET) imaging allows in vivo detection
of fibrillar plaques, a core neuropathological feature of Alzheimer disease (AD). Its …

Primary progressive aphasia comprises a heterogeneous group of neurodegenerative
conditions with diverse clinical profiles and underlying pathological substrates. A major …

Importance One characteristic histopathological event in Alzheimer disease (AD) is cerebral
amyloid aggregation, which can be detected by biomarkers in cerebrospinal fluid (CSF) and …

Objective To assess the impact of new clinical diagnostic criteria for frontotemporal dementia
(FTD) syndromes, including primary progressive aphasias (PPA), on prior clinical diagnosis …

Objective To estimate the prevalence of amyloid positivity, defined by positron emission
tomography (PET)/cerebrospinal fluid (CSF) biomarkers and/or neuropathological examination, …

Purpose The International Consensus Criteria for the diagnosis of primary progressive
aphasia (PPA; Gorno-Tempini et al., 2011) propose apraxia of speech (AOS) as 1 of 2 core …

Background Clinical differentiation between Alzheimer's disease (AD) and behavioural-variant
frontotemporal dementia (bvFTD) is challenging due to overlapping clinical features at …

Disturbed emotion processing and difficulty with social interactions are present to variable
degrees in dementia. They are characteristic features of frontotemporal dementia, whereas …

Differentiation of logopenic (lvPPA) and nonfluent/agrammatic (nfvPPA) variants of Primary
Progressive Aphasia is important yet remains challenging since it hinges on expert based …

… Cristian E. Leyton contributed to design and conceptualization of the study, analysis and
interpretation of data, drafting and revision of the manuscript. Sharpley Hsieh contributed to …