For a decade, The Cancer Genome Atlas (TCGA) program collected clinicopathologic
annotation data along with multi-platform molecular profiles of more than 11,000 human tumors …

Purpose E75 is an immunogenic peptide from the HER2/neu protein that is highly
expressed in breast cancer. We are conducting a clinical trial of an E75 granulocyte-macrophage …

Importance African Americans have the highest breast cancer mortality rate. Although racial
difference in the distribution of intrinsic subtypes of breast cancer is known, it is unclear if …

The identification of extensive genetic heterogeneity in human breast carcinomas poses a
significant challenge for designing effective treatment regimens. Significant genomic evolution …

Motivation: Pathway modeling requires the integration of multiple data including prior
knowledge. In this study, we quantitatively assess the application of Gene Ontology (GO)-derived …

Matrix metalloproteinase (MMP) 2 and 9 are involved in cancer invasion and metastasis, and
increased levels occur in serum and plasma of breast cancer (BC) patients. It is, however, …

Background Determination of estrogen receptor (ER), progesterone receptor (PR), and human
epidermal growth factor receptor 2 (HER2) status is standard for predicting prognosis and …

Purpose: To evaluate the rapid parathyroid hormone assay (rPTH) as a perioperative tool in
predicting postoperative symptomatic hypocalcemia following thyroidectomy. Methods: We …

Background Although diagnosed less often, breast cancer in African American women (AAW)
displays different characteristics compared to breast cancer in Caucasian women (CW), …

Importance Disparities in survival exist between non-Hispanic Black (hereafter, Black) and
non-Hispanic White (hereafter, White) patients with uterine cancer. Objective To investigate …