User profiles for Christopher M Waldmann

Christopher M. Waldmann

Ph.D. in Chemistry, University Medical Center Mainz, Germany
Verified email at unimedizin-mainz.de
Cited by 1137

In vivo imaging of mitochondrial membrane potential in non-small-cell lung cancer

M Momcilovic, A Jones, ST Bailey, CM Waldmann, R Li… - Nature, 2019 - nature.com
Mitochondria are essential regulators of cellular energy and metabolism, and have a crucial
role in sustaining the growth and survival of cancer cells. A central function of mitochondria …

Production of diverse PET probes with limited resources: 24 18F-labeled compounds prepared with a single radiosynthesizer

J Collins, CM Waldmann, C Drake… - Proceedings of the …, 2017 - National Acad Sciences
New radiolabeled probes for positron-emission tomography (PET) are providing an ever-increasing
ability to answer diverse research and clinical questions and to facilitate the …

[HTML][HTML] The search for an alternative to [68Ga] Ga-DOTA-TATE in neuroendocrine tumor theranostics: current state of 18F-labeled somatostatin analog development

CM Waldmann, AD Stuparu, RM van Dam, R Slavik - Theranostics, 2019 - ncbi.nlm.nih.gov
The trend to inform personalized molecular radiotherapy with molecular imaging diagnostics,
a concept referred to as theranostics, has transformed the field of nuclear medicine in …

[HTML][HTML] Image quality analysis of 44Sc on two preclinical PET scanners: a comparison to 68Ga

…, S Michels, MA Hoffmann, M Piel, CM Waldmann… - EJNMMI physics, 2020 - Springer
Background 44 Sc has been increasingly investigated as a potential alternative to 68 Ga in
the development of tracers for positron emission tomography (PET). The lower mean positron …

A dual-modality linker enables site-specific conjugation of antibody fragments for 18F-immuno-PET and fluorescence imaging

KA Zettlitz, CM Waldmann, WTK Tsai… - Journal of Nuclear …, 2019 - Soc Nuclear Med
Antibody-based dual-modality (PET/fluorescence) imaging enables both presurgery antigen-specific
immuno-PET for noninvasive whole-body evaluation and intraoperative …

An automated synthesizer for electrochemical 18F-fluorination of organic compounds

CM Waldmann, A Lebedev, N Allison… - Applied Radiation and …, 2017 - Elsevier
Electrochemical 18 F-fluorination of organic compounds provides a means to synthesize
Positron-Emission-Tomography (PET) tracers difficult to obtain otherwise. Here, the first …

An Automated Multidose Synthesis of the Potentiometric PET Probe 4-[18F]Fluorobenzyl-Triphenylphosphonium ([18F]FBnTP)

CM Waldmann, A Gomez, P Marchis, ST Bailey… - Molecular Imaging and …, 2018 - Springer
Purpose The aim of this study was the automated synthesis of the mitochondrial membrane
potential sensor 4-[ 18 F]fluorobenzyl-triphenylphosphonium ([ 18 F]FBnTP) on a …

Electrochemical no-carrier-added radiofluorination of thioethers

…, T Holloway, A Gomez, A Rios, CM Waldmann… - Journal of Fluorine …, 2022 - Elsevier
We report a method for no-carrier-added radiofluorination of thioethers, which are promising
candidates for new Positron Emission Tomography tracers. For the first time > 100 MBq of …

Novel fluorine-18 labeled 5-(1-pyrrolidinylsulfonyl)-7-azaisatin derivatives as potential PET tracers for in vivo imaging of activated caspases in apoptosis

CM Waldmann, S Hermann, A Faust, B Riemann… - Bioorganic & Medicinal …, 2015 - Elsevier
The programmed type I cell death, defined as apoptosis, is induced by complex regulated
signaling pathways that trigger the intracellular activation of executioner caspases-3, -6 and -7…

Automation of a positron-emission tomography (PET) radiotracer synthesis protocol for clinical production

E Schopf, CM Waldmann, J Collins, C Drake… - JoVE (Journal of …, 2018 - jove.com
The development of new positron-emission tomography (PET) tracers is enabling researchers
and clinicians to image an increasingly wide array of biological targets and processes. …