Membranous NECTIN-4 expression frequently decreases during metastatic spread of urothelial carcinoma and is associated with enfortumab vedotin resistance

…, T Büttner, O Hahn, V Grünwald, C Darr… - Clinical Cancer …, 2023 - AACR
Purpose: The antibody–drug conjugate enfortumab vedotin (EV) releases a cytotoxic agent
into tumor cells via binding to the membrane receptor NECTIN-4. EV was recently approved …

[HTML][HTML] Metastatic prostate cancer—a review of current treatment options and promising new approaches

P Posdzich, C Darr, T Hilser, M Wahl, K Herrmann… - Cancers, 2023 - mdpi.com
Simple Summary Prostate cancer is the most common tumor in men. Although there have
been many new developments in the last few years, metastatic castration resistant prostate …

[HTML][HTML] High fibroblast-activation-protein expression in castration-resistant prostate cancer supports the use of FAPI-molecular theranostics

C Kesch, L Yirga, K Dendl, A Handke, C Darr… - European journal of …, 2021 - Springer
Purpose To evaluate fibroblast-activation-protein (FAP) expression in different clinical stages
of prostate cancer (PC) with regards to utility of [ 68 Ga]Ga-FAPI-04 PET/CT imaging in …

[PDF][PDF] The fake one is the real one: Finstas, authenticity, and context collapse in teen friend groups

CR Darr, EF Doss - Journal of Computer-Mediated …, 2022 - academic.oup.com
Research has shown that as individuals—particularly teenagers—navigate social media,
they value authenticity, typically understood as congruence between their online and offline …

Detection of significant prostate cancer using target saturation in transperineal magnetic resonance imaging/transrectal ultrasonography–fusion biopsy

…, L Püllen, H Reis, A Panic, C Kesch, C Darr… - European Urology …, 2021 - Elsevier
Background Multiparametric magnetic resonance imaging (mpMRI) and targeted biopsies (TBs)
facilitate accurate detection of significant prostate cancer (sPC). However, it remains …

Robotic thoracic surgery results in shorter hospital stay and lower postoperative pain compared to open thoracotomy: a matched pairs analysis

C Darr, D Cheufou, G Weinreich, T Hachenberg… - Surgical …, 2017 - Springer
Background To evaluate postoperative pain intensity and length of hospital stay after open
or robotic thoracic surgery in a standardized postoperative pain therapy setting. Methods In …

Retroperitoneal versus transperitoneal robotic partial nephrectomy: a multicenter matched-pair analysis

NN Harke, C Darr, JP Radtke, N von Ostau… - European urology …, 2021 - Elsevier
Background With increasing acceptance of robotic partial nephrectomy over the last decade,
there is an ongoing discussion about the transperitoneal versus retroperitoneal access. …

Identification of the optimal candidates for nodal staging with extended pelvic lymph node dissection among prostate cancer patients who underwent preoperative …

…, L Bianchi, L Afferi, C Kesch, C Darr… - European Urology …, 2023 - Elsevier
Background Although the therapeutic role of extended pelvic lymph node dissection (ePLND)
in patients with prostate cancer (PCa) is still under debate, this procedure is recommended …

Intraoperative 68Ga-PSMA Cerenkov luminescence imaging for surgical margins in radical prostatectomy: a feasibility study

C Darr, NN Harke, JP Radtke, L Yirga… - Journal of Nuclear …, 2020 - Soc Nuclear Med
Our objective was to assess the feasibility and accuracy of Cerenkov luminescence imaging
(CLI) for assessment of surgical margins intraoperatively during radical prostatectomy. …

[HTML][HTML] Enfortumab vedotin in metastatic urothelial carcinoma: survival and safety in a European multicenter real-world patient cohort

…, A Hassler, BA Hadaschik, V Grünwald, C Darr - European Urology Open …, 2023 - Elsevier
… Tauber r , Richard Cathomas s , Luisa Hofer t , Günter Niegisch u … Christopher Darr y …
Christopher Darr has received advisory board and speaker honoraria and travel fees from …