Background Fluorine-18–sodium fluoride ( 18 F-NaF) uptake is a marker of active vascular
calcification associated with high-risk atherosclerotic plaque. Objectives In patients with …

Background: Valvular calcification is central to the pathogenesis and progression of aortic
stenosis, with preclinical and observational studies suggesting that bone turnover and …

Background : Bioprosthetic aortic valve degeneration is increasingly common, often unheralded,
and can have catastrophic consequences. Objectives : The authors sought to assess …

Background— Combined positron emission tomography (PET) and computed tomography (CT)
can assess both anatomy and biology of carotid atherosclerosis. We sought to assess …

Objective Maladaptive repair contributes towards the development of heart failure following
myocardial infarction (MI). The α v β 3 integrin receptor is a key mediator and determinant of …

Background— 18F-Fluoride positron emission tomography (PET) and computed tomography
(CT) can measure disease activity and progression in aortic stenosis. Our objectives were …

Myocardial infarction (MI) is one of the leading causes of death worldwide, and inflammation
is central to tissue response and patient outcomes. The 18-kDa translocator protein (TSPO) …

Objectives Intraplaque angiogenesis and inflammation are key promoters of atherosclerosis
and are mediated by the alpha-V beta-3 (α v β 3 ) integrin pathway. We investigated the …

Objectives Computed tomography (CT) can perform comprehensive cardiac imaging. We
compared CT coronary angiography (CTCA) and CT myocardial perfusion (CTP) with 15 O-…

Neuroinflammation is associated with a number of brain diseases, making it a common
feature of cerebral pathology. Among the best-known biomarkers for neuroinflammation in …