Nonequilibrium mechanics of active cytoskeletal networks
Cells both actively generate and sensitively react to forces through their mechanical framework,
the cytoskeleton, which is a nonequilibrium composite material including polymers and …
the cytoskeleton, which is a nonequilibrium composite material including polymers and …
Direct observation of kinesin stepping by optical trapping interferometry
Do biological motors move with regular steps? To address this question, we constructed
instrumentation with the spatial and temporal sensitivity to resolve movement on a molecular …
instrumentation with the spatial and temporal sensitivity to resolve movement on a molecular …
Economic impacts from the promotion of renewable energy technologies: The German experience
The allure of an environmentally benign, abundant, and cost-effective energy source has
led an increasing number of industrialized countries to back public financing of renewable …
led an increasing number of industrialized countries to back public financing of renewable …
[HTML][HTML] Laser-induced heating in optical traps
EJG Peterman, F Gittes, CF Schmidt - Biophysical journal, 2003 - cell.com
In an optical tweezers experiment intense laser light is tightly focused to intensities of MW/cm
2 in order to apply forces to submicron particles or to measure mechanical properties of …
2 in order to apply forces to submicron particles or to measure mechanical properties of …
Rapid chiral assembly of rigid DNA building blocks for molecular nanofabrication
…, CF Tardin, CM Erben, RM Berry, CF Schmidt… - Science, 2005 - science.org
Practical components for three-dimensional molecular nanofabrication must be simple to
produce, stereopure, rigid, and adaptable. We report a family of DNA tetrahedra, less than 10 …
produce, stereopure, rigid, and adaptable. We report a family of DNA tetrahedra, less than 10 …
Effect of early vs delayed initiation of renal replacement therapy on mortality in critically ill patients with acute kidney injury: the ELAIN randomized clinical trial
A Zarbock, JA Kellum, C Schmidt, H Van Aken… - Jama, 2016 - jamanetwork.com
Importance Optimal timing of initiation of renal replacement therapy (RRT) for severe acute
kidney injury (AKI) but without life-threatening indications is still unknown. Objective To …
kidney injury (AKI) but without life-threatening indications is still unknown. Objective To …
Interference model for back-focal-plane displacement detection in optical tweezers
F Gittes, CF Schmidt - Optics letters, 1998 - opg.optica.org
The lateral position of an optically trapped object in a microscope can be monitored with a
quadrant photodiode to within nanometers or better by measurement of intensity shifts in the …
quadrant photodiode to within nanometers or better by measurement of intensity shifts in the …
The bipolar mitotic kinesin Eg5 moves on both microtubules that it crosslinks
During cell division, mitotic spindles are assembled by microtubule-based motor proteins 1 ,
2 . The bipolar organization of spindles is essential for proper segregation of chromosomes, …
2 . The bipolar organization of spindles is essential for proper segregation of chromosomes, …
Microscopic viscoelasticity: shear moduli of soft materials determined from thermal fluctuations
We describe a high-resolution, high-bandwidth technique for determining the local viscoelasticity
of soft materials such as polymer gels. Loss and storage shear moduli are determined …
of soft materials such as polymer gels. Loss and storage shear moduli are determined …
[HTML][HTML] Prevention of cardiac surgery-associated AKI by implementing the KDIGO guidelines in high risk patients identified by biomarkers: the PrevAKI randomized …
M Meersch, C Schmidt, A Hoffmeier, H Van Aken… - Intensive care …, 2017 - Springer
Purpose Care bundles are recommended in patients at high risk for acute kidney injury (AKI),
although they have not been proven to improve outcomes. We sought to establish the …
although they have not been proven to improve outcomes. We sought to establish the …