IL-22 is increased in active Crohn's disease and promotes proinflammatory gene expression and intestinal epithelial cell migration

…, B Göke, CJ Auernhammer… - American Journal …, 2006 - journals.physiology.org
IL-22 is produced by activated T cells and signals through a receptor complex consisting of
IL-22R1 and IL-10R2. The aim of this study was to analyze IL-22 receptor expression, signal …

The role of the novel Th17 cytokine IL-26 in intestinal inflammation

…, EN De Toni, B Göke, HM Diepolder, CJ Auernhammer… - Gut, 2009 - gut.bmj.com
Background and aims: Interleukin 26 (IL-26), a novel IL-10-like cytokine without a murine
homologue, is expressed in T helper 1 (Th1) and Th17 cells. Currently, its function in human …

Consensus guidelines for the management of patients with digestive neuroendocrine tumors–well-differentiated jejunal-ileal tumor/carcinoma

…, B Wiedenmann, R Arnold, C Auernhammer… - …, 2008 - karger.com
Barbro Eriksson a Günter Klöppel b Eric Krenning c Hakan Ahlman d Ursula Plöckinger e
Bertram Wiedenmann e Rudolf Arnold f Christoph Auernhammer g Meike Körner h Guido …

68Ga-DOTATATE PET/CT for the early prediction of response to somatostatin receptor–mediated radionuclide therapy in patients with well-differentiated …

AR Haug, CJ Auernhammer, B Wängler… - Journal of nuclear …, 2010 - Soc Nuclear Med
We aimed to evaluate 68 Ga-DOTATATE PET/CT for the early prediction of time to progression
and clinical outcome after a first cycle of peptide receptor radionuclide treatment (PRRT) …

IL-28A and IL-29 mediate antiproliferative and antiviral signals in intestinal epithelial cells and murine CMV infection increases colonic IL-28A expression

…, B Adler, CJ Auernhammer… - American Journal …, 2005 - journals.physiology.org
Human cytomegalovirus virus (CMV) is a major cause of morbidity and mortality in
immunocompromised individuals. Recently, a novel group of cytokines [interleukin (IL)-28A/B and IL-…

Intraindividual comparison of 68Ga-DOTA-TATE and 18F-DOPA PET in patients with well-differentiated metastatic neuroendocrine tumours

A Haug, CJ Auernhammer, B Wängler, R Tiling… - European journal of …, 2009 - Springer
Aim To compare the diagnostic impact of 68 Ga-DOTA-TATE and 18 F-DOPA PET in the
diagnosis of well-differentiated metastatic neuroendocrine tumours (NET). Methods PET/CT …

The role of 68Ga-DOTATATE PET/CT in suspected neuroendocrine tumors

…, R Cindea-Drimus, CJ Auernhammer… - Journal of nuclear …, 2012 - Soc Nuclear Med
In patients with suspected but yet not localized neuroendocrine tumors (NETs), early
diagnosis or reliable exclusion is crucial for optimal individual prognosis and therapy. Despite …

The novel mTOR inhibitor RAD001 (everolimus) induces antiproliferative effects in human pancreatic neuroendocrine tumor cells

…, G Spöttl, HHD Meyer, CJ Auernhammer - …, 2007 - karger.com
Background/Aim: Tumors exhibiting constitutively activated PI (3) K/Akt/mTOR signaling are
hypersensitive to mTOR inhibitors such as RAD001 (everolimus) which is presently being …

Compensatory activation of Akt in response to mTOR and Raf inhibitors–a rationale for dual-targeted therapy approaches in neuroendocrine tumor disease

…, S Brand, B Göke, J Lichtl, G Spöttl, CJ Auernhammer - Cancer letters, 2010 - Elsevier
Several studies have established a link between aberrant PI(3)K–Akt–mTOR- and Ras–Raf–MEK–Erk1/2
signaling and neuroendocrine tumor disease. In this study, we comparatively …

IL-22-mediated liver cell regeneration is abrogated by SOCS-1/3 overexpression in vitro

…, WE Thasler, CJ Auernhammer - American Journal …, 2007 - journals.physiology.org
The IL-10-like cytokine IL-22 is produced by activated T cells. In this study, we analyzed the
role of this cytokine system in hepatic cells. Expression studies were performed by RT-PCR …