En bloc resection of urothelium carcinoma of the bladder (EBRUC): a European multicenter study to compare safety, efficacy, and outcome of laser and electrical en …

…, R Hurle, M Wolters, M Abbas, CA von Klot… - World journal of …, 2015 - Springer
Purpose En bloc resection of bladder tumors (ERBT) may improve staging quality and
perioperative morbidity and influence tumor recurrence. This study was designed to evaluate the …

Initial experience with volumetric 68Ga-PSMA I&T PET/CT for assessment of whole-body tumor burden as a quantitative imaging biomarker in patients with prostate …

S Schmuck, CA von Klot, C Henkenberens… - Journal of Nuclear …, 2017 - Soc Nuclear Med
A quantitative imaging biomarker is desirable to provide a comprehensive measure of whole-body
tumor burden in patients with metastatic prostate cancer, and to standardize the …

Enzalutamide antitumour activity against metastatic castration-resistant prostate cancer previously treated with docetaxel and abiraterone: a multicentre analysis

…, D Lorente, M Retz, AS Merseburger, CA Von Klot… - European urology, 2015 - Elsevier
Background The degree of antitumour activity of enzalutamide following disease progression
on docetaxel and abiraterone remains controversial. Objective To examine the effect of …

Comparison of standard and delayed imaging to improve the detection rate of [68Ga]PSMA I&T PET/CT in patients with biochemical recurrence or prostate-specific …

S Schmuck, S Nordlohne, CA von Klot… - European journal of …, 2017 - Springer
Purpose The aim of this study was to assess the value of dual-time point imaging in PET/CT
for detection of biochemically recurrent or persistent prostate cancer, using the prostate-…

[PDF][PDF] 68Ga-PSMA ligand PET/CT-based radiotherapy in locally recurrent and recurrent oligometastatic prostate cancer

C Henkenberens, CA von Klot, TL Ross… - Strahlenther …, 2016 - researchgate.net
Purpose The goal of this work was to evaluate the early efficacy of 68Ga-PSMA ligand PET/CT
imaging for radiotherapy of locally recurrent and/or oligometastatic prostate cancer. …

Patterns of progression after 68Ga-PSMA-ligand PET/CT-guided radiation therapy for recurrent prostate cancer

A Soldatov, CAJ von Klot, D Walacides, T Derlin… - International Journal of …, 2019 - Elsevier
Purpose To determine the patterns of progression after 68 Ga prostate-specific membrane
antigen (PSMA)-ligand positron emission tomography (PET)/computed tomography (CT)-…

An update on enzalutamide in the treatment of prostate cancer

…, GP Haas, CA von Klot - Therapeutic advances in …, 2015 - journals.sagepub.com
Enzalutamide is an oral androgen receptor inhibitor that targets multiple steps in the
androgen receptor signaling pathway. In the randomized phase III AFFIRM study, significant …

Multiple time-point 68Ga-PSMA I&T PET/CT for characterization of primary prostate cancer: value of early dynamic and delayed imaging

…, M Mamach, F Wilke, CA von Klot… - Clinical Nuclear …, 2017 - journals.lww.com
Purpose The aims of this study were to gain mechanistic insights into prostate cancer
biology using dynamic imaging and to evaluate the usefulness of multiple time-point 68 Ga–…

Androgen deprivation therapy as backbone therapy in the management of prostate cancer

…, A Alcaraz, CA von Klot - OncoTargets and therapy, 2016 - Taylor & Francis
Androgen deprivation therapy (ADT) is well established as a backbone therapy for metastatic
prostate cancer (mPCa), and both European and American guidelines emphasize the …

PSA-stratified detection rates for [68Ga]THP-PSMA, a novel probe for rapid kit-based 68Ga-labeling and PET imaging, in patients with biochemical recurrence after …

…, ACA Walte, K Hueper, CA von Klot… - European Journal of …, 2018 - Springer
Purpose [ 68 Ga]Tris(hydroxypyridinone)(THP)-PSMA is a novel radiopharmaceutical for
one-step kit-based radiolabelling, based on direct chelation of 68 Ga 3+ at low concentration, …